سعر البروسباير 0.5مجم/مل امبولات للحقن الوريدي 2026

Egyptian alprostadil (prostaglandin E1) 0.5 mg/ml concentrate in ampoules for intravenous infusion, by Delta Pharma (Inspire).

• Palliative therapy to temporarily maintain patency of the ductus arteriosus until surgery in neonates with congenital heart defects dependent on the ductusPopulation: NeonatesDailyMed (NLM)

• Common: fever (about 14%), apnea (about 12%), flushing (about 10%), bradycardia (about 7%), seizures (about 4%), hypotension (about 4%), tachycardia (about 3%), diarrhea (about 2%).International label, equivalent formulation · DailyMed (NLM)

• None stated in the US label.International label, equivalent formulation · DailyMed (NLM)

• Boxed warning: apnea occurs in about 10-12% of neonates with congenital heart defects treated with alprostadil, most often in those under 2 kg and usually in the first hour of infusion; use only where ventilatory assistance is immediately available.International label, equivalent formulation · DailyMed (NLM)
• Prolonged infusion (beyond about 120 hours) has been associated with gastric outlet obstruction from antral hyperplasia, and long-term infusion with cortical proliferation of long bones.International label, equivalent formulation · DailyMed (NLM)
• Inhibits platelet aggregation; use cautiously in neonates with bleeding tendencies. Not indicated for respiratory distress syndrome.International label, equivalent formulation · DailyMed (NLM)

• Alprostadil: Relaxes smooth muscle of the ductus arteriosus (US Prostin VR Pediatric label).