سعر اسباتريند 6 اكياس 2024

Aspatrend granules, 6 sachets (Trend Pharm, manufactured by Medizen Pharmaceutical Industries, Egypt): L-ornithine-L-aspartate (3 g per sachet according to an Egyptian online pharmacy), an ammonia-lowering amino-acid salt used in liver disease with hepatic encephalopathy.

• Treatment of concomitant diseases and sequelae of impaired hepatic detoxification (e.g. liver cirrhosis) with symptoms of latent or manifest hepatic encephalopathy.Population: Adults (Merz prescribing information)

• Uncommon: nausea, vomiting, stomach ache, flatulence, diarrhoea; very rare: pain in the limbs. Gastrointestinal effects are usually transient.International label, equivalent formulation

• Hypersensitivity to L-ornithine-L-aspartate or any excipient.International label, equivalent formulation
• Severe renal impairment (serum creatinine above 3 mg/100 ml).International label, equivalent formulation

• Reference granules contain excipients such as fructose (and, in one variant, aspartame, a phenylalanine source relevant in phenylketonuria); Egyptian excipients were not verified.International label, equivalent formulation

• No data in pregnancy; use should be avoided unless considered necessary after careful benefit-risk assessment.International label, equivalent formulation
• Avoid during breast-feeding unless considered necessary.International label, equivalent formulation

• L-ornithine-L-aspartate (ornithine aspartate): Ornithine and aspartate act on the two main ammonia detoxification pathways: ornithine activates and is a substrate of hepatic urea synthesis, and both supply glutamate for glutamine synthesis, lowering blood ammonia.