سعر افانجوي 50 مجم 4 اقراص 2022

Avanjoy 50 mg (Eva Pharma): avanafil 50 mg oral tablets, a phosphodiesterase type 5 (PDE5) inhibitor for erectile dysfunction; pack of 4 tablets.

• Treatment of erectile dysfunctionPopulation: Adult malesDailyMed (US National Library of Medicine)

• Most common (>=2%): headache (5.1-10.5%), flushing (3.2-4.3%), nasal congestion, nasopharyngitis and back pain. Postmarketing: serious cardiovascular and cerebrovascular events in patients with pre-existing risk factors.International label, equivalent formulation · DailyMed (US National Library of Medicine)

• Use with any form of organic nitrate (regularly or intermittently) is contraindicated; if nitrates are medically necessary in a life-threatening situation, at least 12 hours should elapse after the last avanafil dose, under close supervision.International label, equivalent formulation · DailyMed (US National Library of Medicine)
• Known hypersensitivity to any component of the tablet.International label, equivalent formulation · DailyMed (US National Library of Medicine)
• Concomitant guanylate cyclase stimulators such as riociguat or vericiguat.International label, equivalent formulation · DailyMed (US National Library of Medicine)

• Cardiovascular risk: not for men in whom sexual activity is inadvisable; not recommended (not studied) after MI, stroke, life-threatening arrhythmia or coronary revascularisation within 6 months, resting hypotension (<90/50 mmHg) or hypertension (>170/100 mmHg), unstable angina, angina with intercourse, or NYHA class 2 or greater heart failure.International label, equivalent formulation · DailyMed (US National Library of Medicine)
• Prolonged erection over 4 hours or priapism requires immediate medical assistance; use with caution with penile anatomical deformation or conditions predisposing to priapism (sickle cell anaemia, multiple myeloma, leukaemia).International label, equivalent formulation · DailyMed (US National Library of Medicine)
• Sudden loss of vision (possible NAION) or sudden decrease/loss of hearing: stop the medicine and seek prompt medical attention.International label, equivalent formulation · DailyMed (US National Library of Medicine)

• NitratesContraindicated: avanafil potentiates the hypotensive effect of nitrates.DailyMed (US National Library of Medicine)
• Strong CYP3A4 inhibitors (ketoconazole, ritonavir, clarithromycin, itraconazole and others)Do not use avanafil; ketoconazole increased avanafil AUC 13-fold.DailyMed (US National Library of Medicine)
• Moderate CYP3A4 inhibitors (erythromycin, aprepitant, diltiazem, fluconazole, verapamil and others)Maximum avanafil dose 50 mg, not more than once every 24 hours.DailyMed (US National Library of Medicine)

• Not indicated for use in females; no human pregnancy data; no adverse developmental outcomes in rat and rabbit studies at about 8 and 6 times the maximum recommended human dose exposure.International label, equivalent formulation · DailyMed (US National Library of Medicine)
• Not indicated for use in females; no information on presence in human or animal milk or effects on the breastfed child.International label, equivalent formulation · DailyMed (US National Library of Medicine)

• Avanafil: Selective inhibitor of cGMP-specific PDE5; enhances the nitric oxide/cGMP pathway so that sexual stimulation produces an erection (US label).