سعر بي سي جي مصل 1مجم امبول 2022

BCG (Bacillus Calmette-Guérin) tuberculosis vaccine, 1 mg ampoule, pack of 1 (VACSERA, Egypt). Strain, presentation (freeze-dried or not), number of doses per ampoule and route are not stated by the Egyptian source.

• Active immunisation against tuberculosis (according to national official recommendations)electronic medicines compendium (emc)

• Expected reaction: induration at the injection site followed by a local lesion that may ulcerate some weeks later and heal over months leaving a small flat scar; local erythema, tenderness and regional lymph node enlargement under 1 cm may occur.General active-ingredient information · electronic medicines compendium (emc)
• Uncommon: regional lymph node enlargement over 1 cm, headache, fever, injection-site ulceration and discharge. Rare: suppurative lymphadenitis, osteitis, osteomyelitis, injection-site abscess, allergic and anaphylactic reactions.General active-ingredient information · electronic medicines compendium (emc)

• Hypersensitivity to the vaccine or its excipients; postpone vaccination during acute severe febrile illness or generalised infected skin conditions.General active-ingredient information · electronic medicines compendium (emc)
• Do not give to persons on systemic corticosteroids or other immunosuppressive treatment including radiotherapy, or to infants exposed to immunosuppressive treatment in utero or via breastfeeding (e.g. maternal TNF-alpha antagonists).General active-ingredient information · electronic medicines compendium (emc)
• Do not give to persons with malignant conditions (e.g. lymphoma, leukaemia, Hodgkin disease), primary or secondary immunodeficiency, or HIV infection, including infants born to HIV-positive mothers; generalised BCG infection is possible in the immunosuppressed.General active-ingredient information · electronic medicines compendium (emc)

• Tuberculin-positive persons do not require the vaccine; vaccinating them may cause a severe local reaction.General active-ingredient information · electronic medicines compendium (emc)
• Injection that is too deep increases the risk of discharging ulcer, lymphadenitis and abscess; the vaccine must never be given intravascularly.General active-ingredient information · electronic medicines compendium (emc)
• Consider the risk of apnoea and respiratory monitoring for 48-72 hours in very premature infants (born at 28 weeks or less); immune reconstitution inflammatory syndrome has been reported in previously BCG-vaccinated immunodeficient children after starting antiretroviral or immune therapy.General active-ingredient information · electronic medicines compendium (emc)

• Other vaccines (inactivated or live, e.g. MMR)May be given concurrently but not in the same arm; if not given at the same time, allow at least four weeks between two live vaccines; avoid further vaccination in the BCG arm for 3 months (risk of regional lymphadenitis).electronic medicines compendium (emc)
• Anti-tuberculosis drugsVaccine should not be given to patients receiving anti-tuberculosis drugs; the Danish 1331 strain is resistant to pyrazinamide and of intermediate susceptibility to isoniazid (strain-specific data).electronic medicines compendium (emc)

• No harmful effects to the foetus have been associated with the vaccine, but vaccination is not recommended during pregnancy; in areas of high tuberculosis risk it may be given if benefit outweighs risk.General active-ingredient information · electronic medicines compendium (emc)
• No harmful effects to the breastfed child have been associated with the vaccine, but vaccination of the mother is not recommended during lactation unless the benefit outweighs the risk in high-risk areas.General active-ingredient information · electronic medicines compendium (emc)

• BCG vaccine (live attenuated Mycobacterium bovis BCG): Elicits a cell-mediated immune response that confers a variable degree of protection against infection with Mycobacterium tuberculosis; duration of immunity is not known (some indication of waning after 10 years).