سعر بكلوزون بخاخ للاستنشاق 50مكجم/جرعة 200 بخة 2024

Beclosone pressurised metered-dose inhaler by the Arab Drug Company (ADCO, Egypt): beclometasone dipropionate 50 micrograms per actuation, 200 actuations; inhaled corticosteroid for prophylactic asthma management.

• Prophylactic management of mild, moderate or severe asthmaPopulation: Adults and childrenelectronic medicines compendium (emc)

• Very common: oral candidiasis (mouth and throat). Common: hoarseness, throat irritation. Uncommon: rash, urticaria, pruritus, erythema. Very rare: oedema of eyes/face/lips/throat, adrenal suppression, growth retardation, decreased bone density, cataract, glaucoma, paradoxical bronchospasm. Unknown: psychomotor hyperactivity, sleep disorders, anxiety, depression, aggression, headache, blurred vision, nausea.International label, equivalent formulation · electronic medicines compendium (emc)

• Hypersensitivity to beclometasone dipropionate or any excipient.International label, equivalent formulation · electronic medicines compendium (emc)

• Not for relief of acute asthma symptoms; patients need a short-acting bronchodilator available. Use regularly even when asymptomatic; do not stop abruptly.International label, equivalent formulation · electronic medicines compendium (emc)
• Increasing use of reliever indicates deteriorating control and need for reassessment; severe exacerbations need increased corticosteroid therapy.International label, equivalent formulation · electronic medicines compendium (emc)
• Systemic effects possible at high doses for prolonged periods: adrenal suppression, growth retardation in children, decreased bone mineral density, cataract, glaucoma, psychological/behavioural effects; titrate to the lowest effective dose and monitor height in children.International label, equivalent formulation · electronic medicines compendium (emc)

• Strong CYP3A inhibitors (e.g. ritonavir, cobicistat)Beclometasone is less dependent on CYP3A than some corticosteroids, but systemic effects cannot be excluded; use with caution and monitoring.electronic medicines compendium (emc)
• Disulfiram, metronidazoleTheoretical interaction in sensitive patients because the UK product contains a small amount of ethanol; Egyptian excipients not verified.electronic medicines compendium (emc)

• No human experience in pregnancy; use only if expected benefit to the mother outweighs potential risk to the fetus. Corticosteroids in pregnant animals can cause cleft palate and intra-uterine growth retardation after high systemic exposure; inhaled delivery avoids high systemic exposure.International label, equivalent formulation · electronic medicines compendium (emc)
• Reasonable to assume secretion into milk, but low potential for significant levels at inhaled doses; use only if benefit outweighs risk.International label, equivalent formulation · electronic medicines compendium (emc)

• Beclometasone dipropionate: Pro-drug with weak glucocorticoid-receptor affinity, hydrolysed by esterases to the active metabolite beclometasone-17-monopropionate, which has potent topical anti-inflammatory activity (UK SmPC).