سعر كابيستابين فارماكير 500مجم 120 قرص 2024

Capecitabine Pharmacare 500 mg 120 f.c. tabs.: Capecitabine 500 mg film-coated tablets (Pharmacare Premium Ltd. > Pharma Cruise Medical).

• Adjuvant Stage III colon cancer (single agent or combination); perioperative locally advanced rectal cancer (US labeling).Population: AdultsDailyMed / FDA
• Breast cancer per US Capecitabine labeling.Population: AdultsDailyMed / FDA
• Gastric, esophageal, or GEJ cancer; pancreatic cancer (US Capecitabine labeling).Population: AdultsDailyMed / FDA

• See full USPI contraindications (hypersensitivity and other labeled contraindications).International label, same formulation · DailyMed / FDA

• Boxed warning: increased bleeding risk with oral vitamin K antagonists; monitor INR more frequently (US DailyMed).International label, same formulation · DailyMed / FDA
• Serious adverse reactions from DPD deficiency; not recommended in complete DPD deficiency (US DailyMed).International label, same formulation · DailyMed / FDA
• Also: cardiotoxicity, diarrhea, dehydration, renal toxicity, serious skin toxicities, hand-foot syndrome, myelosuppression, hyperbilirubinemia, embryo-fetal toxicity (US DailyMed).International label, same formulation · DailyMed / FDA

• Vitamin K antagonists (e.g. warfarin)MajorAltered coagulation/bleeding including death reported; monitor INR and adjust dose (US DailyMed).DailyMed / FDA
• PhenytoinModerateMonitor phenytoin levels and adjust dose when used with capecitabine (US DailyMed).DailyMed / FDA
• Nephrotoxic drugsModerateMonitor for renal toxicity with concomitant nephrotoxic drugs (US DailyMed).DailyMed / FDA

• Can cause fetal harm; advise pregnant women of potential fetal risk (US DailyMed).International label, same formulation · DailyMed / FDA
• Advise not to breastfeed during treatment (US DailyMed).International label, same formulation · DailyMed / FDA

• Capecitabine: Converted enzymatically to 5-fluorouracil in tumour tissue; 5-FU metabolites inhibit thymidylate synthase and disrupt RNA/DNA synthesis (US DailyMed Capecitabine Accord).