سعر كولسيفر 20 قرص مغلف 2023

Mebeverine+sulpiride film-coated tablets for gastrointestinal spasms (Al Rowad).

• Symptomatic treatment of irritable bowel syndrome and related conditions (chronic irritable colon, spastic constipation, mucous/spastic colitis), including colicky abdominal pain, non-specific diarrhoea with or without alternating constipation, and flatulence.Population: Adults with IBS-spectrum symptomsMHRA / Datapharm eMC

• Post-marketing: hypersensitivity including anaphylaxis; skin reactions (urticaria, angioedema, face oedema, exanthema) — frequency not known (UK SmPC).General active-ingredient information · MHRA / Datapharm eMC

• Hypersensitivity to mebeverine or any excipient (UK SmPC).General active-ingredient information · MHRA / Datapharm eMC

• Seek medical advice before use if first presentation of IBS-like symptoms, age >40, rectal bleeding, unexplained weight loss, fever, recent foreign travel, or pregnancy (UK SmPC warnings).General active-ingredient information · MHRA / Datapharm eMC

• Mebeverine is not recommended during pregnancy; limited human data and insufficient animal reproductive toxicity data (UK SmPC 4.6).General active-ingredient information · MHRA / Datapharm eMC
• Mebeverine should not be used during breast-feeding; excretion in human milk unknown (UK SmPC).General active-ingredient information · MHRA / Datapharm eMC

• Mebeverine hydrochloride: Direct relaxant effect on gastrointestinal smooth muscle without anticholinergic systemic effects (UK SmPC).
• Sulpiride: Selective dopamine D2 receptor antagonist; used in some markets for psychosomatic digestive disorders at low dose.