سعر دوبيكسنت 200 مجم 2 سرنجة معبأة مسبقاً للحقن تحت الجلد 2024

Dupixent 200 mg 2 pref. syringe s.c. — Dupilumab (Sanofi > Sanofi Scientific Office).

• Atopic dermatitis: moderate-to-severe AD in patients 6 months and older whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable; can be used with or without topical corticosteroids (US Dupixent label).Population: AdultsDailyMed (NLM)
• Asthma: add-on maintenance treatment of adult and pediatric patients aged 6 years and older with eosinophilic phenotype or with oral corticosteroid-dependent asthma (US Dupixent label). Not for relief of acute bronchospasm.Population: AdultsDailyMed (NLM)
• Chronic rhinosinusitis with nasal polyposis (CRSwNP) and other labeled type-2 inflammatory indications as on the current US Dupixent prescribing information (confirm Egyptian registered indications).Population: AdultsDailyMed (NLM)

• Common adverse reactions vary by indication; frequently include injection-site reactions, conjunctivitis, blepharitis, oral herpes, eosinophilia, and eye pruritus — see full US label tables (US Dupixent label).International label, same product · DailyMed (NLM)

• Known hypersensitivity to dupilumab or any excipients in DUPIXENT (US label).International label, same product · DailyMed (NLM)

• Hypersensitivity reactions including anaphylaxis, AGEP, serum sickness, angioedema, urticaria, rash, erythema nodosum and erythema multiforme have occurred — discontinue if hypersensitivity occurs. Conjunctivitis, keratitis and blepharitis: advise patients to report new eye symptoms. Helminth infections: treat before starting if present; discontinue if infection occurs and does not respond. Avoid live vaccines (US Dupixent label).International label, same product · DailyMed (NLM)

• Available data from case reports and registry with use in pregnant women have not identified a drug-associated risk of major birth defects, miscarriage, or adverse maternal/fetal outcomes; human IgG antibodies cross placenta — clinical relevance unknown. Report pregnancies to the manufacturer pregnancy registry (US Dupixent label — PLLR).International label, same product · DailyMed (NLM)
• No data on presence in human milk; maternal IgG is present in milk. Consider developmental benefits of breastfeeding with mother clinical need (US Dupixent label).International label, same product · DailyMed (NLM)

• Dupilumab: Fully human IgG4 monoclonal antibody that inhibits IL-4 and IL-13 signaling by binding IL-4Rα, reducing type 2 inflammation.