سعر ايزاديكس 5% كريم 20 جم 2022

Fluorouracil 5% topical cream (antimetabolite) for actinic keratoses and superficial basal cell carcinoma, 20 g tube.

• Topical treatment of multiple actinic or solar keratoses.Population: AdultsDailyMed (U.S. NLM)
• Superficial basal cell carcinoma when conventional methods are impractical (5% strength only).Population: AdultsDailyMed (U.S. NLM)

• Local reactions are most common: burning, crusting, allergic contact dermatitis, erosions, erythema, hyperpigmentation, irritation, pain, photosensitivity, pruritus, scarring, rash, soreness and ulceration.International label, same formulation · DailyMed (U.S. NLM)

• Pregnancy (may cause fetal harm).International label, same formulation · DailyMed (U.S. NLM)
• Dihydropyrimidine dehydrogenase (DPD) enzyme deficiency.International label, same formulation · DailyMed (U.S. NLM)
• Known hypersensitivity to fluorouracil or any component.International label, same formulation · DailyMed (U.S. NLM)

• Increased risk of serious toxicity in patients with DPD deficiency; stop use if signs of systemic toxicity appear.International label, same formulation · DailyMed (U.S. NLM)
• Avoid application to mucous membranes; occlusive dressings may increase inflammatory reactions in adjacent normal skin.International label, same formulation · DailyMed (U.S. NLM)
• Minimise exposure to ultraviolet light (sunlight, tanning beds) during treatment.International label, same formulation · DailyMed (U.S. NLM)

• Contraindicated in pregnancy: fluorouracil may cause fetal harm; females of reproductive potential should use effective contraception during treatment.International label, same formulation · DailyMed (U.S. NLM)

• Fluorouracil: Inhibits thymidylate synthase after intracellular activation, disrupting DNA synthesis in rapidly dividing cells.