سعر ازيتيميب 10مجم 10 اقراص 2025

Ezetimibe 10 mg tablets (Ezetimibe; Borg), pack of 10 tablets.

• In combination with a statin, or alone when additional LDL-C lowering therapy is not possible, as an adjunct to diet to reduce elevated LDL-C in adults with primary hyperlipidemia, including heterozygous familial hypercholesterolemia (HeFH).Population: AdultsDailyMed (U.S. National Library of Medicine)
• In combination with a statin as an adjunct to diet to reduce elevated LDL-C in pediatric patients 10 years and older with HeFH.Population: Children 10 years and olderDailyMed (U.S. National Library of Medicine)
• In combination with fenofibrate as an adjunct to diet to reduce elevated LDL-C in adults with mixed hyperlipidemia.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Common adverse reactions (>=2% and greater than placebo) include upper respiratory tract infection, diarrhea, arthralgia, sinusitis, pain in extremity, fatigue and influenza. Post-marketing: thrombocytopenia, pancreatitis, hepatitis, cholelithiasis, hypersensitivity reactions.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to ezetimibe or any excipient. When used with a statin or fenofibrate, refer to that product's contraindications.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Liver enzyme elevations: with a statin, increased transaminases may occur; if ALT or AST >=3 x ULN persists, consider withdrawal of ezetimibe and/or the statin.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Myopathy/rhabdomyolysis has been reported, mostly with a statin; discontinue if myopathy is diagnosed or suspected.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• CyclosporineEzetimibe and cyclosporine exposure may both increase; monitor cyclosporine concentrations.DailyMed (U.S. National Library of Medicine)
• FibratesFibrates may increase cholesterol excretion into bile and lead to cholelithiasis; co-administration with fibrates other than fenofibrate is not recommended.DailyMed (U.S. National Library of Medicine)
• Bile acid sequestrants (e.g., cholestyramine)Decrease ezetimibe exposure; separate administration (see administration).DailyMed (U.S. National Library of Medicine)

• There are insufficient data on ezetimibe use in pregnant women to evaluate drug-associated risk of major birth defects or miscarriage.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• It is not known whether ezetimibe is present in human milk.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Ezetimibe: Inhibits intestinal absorption of cholesterol and related phytosterols (US Zetia label).