سعر فاتلوز 120مجم 10 كبسولات 2022

Orlistat 120 mg oral capsules (Repharma / El-Obour), pack of 10.

• Obesity management, including weight loss and weight maintenance, with a reduced-calorie diet; also to reduce the risk of weight regain after prior weight loss. For obese patients with initial BMI 30 kg/m2 or more, or 27 kg/m2 or more with other risk factors (e.g. hypertension, diabetes, dyslipidaemia).DailyMed (U.S. NLM)

• Gastrointestinal effects from fat malabsorption are most common in year 1: oily spotting (26.6%), flatus with discharge (23.9%), faecal urgency (22.1%), fatty/oily stool (20.0%), oily evacuation (11.9%), increased defecation (10.8%) and faecal incontinence.International label, same formulation · DailyMed (U.S. NLM)

• Pregnancy.International label, same formulation · DailyMed (U.S. NLM)
• Chronic malabsorption syndrome.International label, same formulation · DailyMed (U.S. NLM)
• Cholestasis.International label, same formulation · DailyMed (U.S. NLM)

• Reduces absorption of some fat-soluble vitamins and beta-carotene; advise a multivitamin with fat-soluble vitamins.International label, same formulation · DailyMed (U.S. NLM)
• Rare post-marketing reports of severe liver injury (hepatocellular necrosis, acute hepatic failure, some leading to transplant or death); stop and check liver tests if symptoms of hepatic dysfunction occur.International label, same formulation · DailyMed (U.S. NLM)
• Oxalate nephrolithiasis and oxalate nephropathy with renal failure have been reported; discontinue if oxalate nephropathy develops.International label, same formulation · DailyMed (U.S. NLM)

• CyclosporineReduced cyclosporine plasma levels; do not co-administer simultaneously; give cyclosporine 3 hours after orlistat.DailyMed (U.S. NLM)
• LevothyroxineHypothyroidism reported; give at least 4 hours apart and monitor thyroid function.DailyMed (U.S. NLM)
• Warfarin and other anticoagulantsVitamin K absorption may decrease; INR changes reported; monitor coagulation parameters closely.DailyMed (U.S. NLM)

• Contraindicated in pregnancy: weight loss offers no potential benefit to a pregnant woman and may result in fetal harm.International label, same formulation · DailyMed (U.S. NLM)
• Not known whether orlistat is present in human milk; use caution in nursing women.International label, same formulation · DailyMed (U.S. NLM)

• Orlistat: Reversibly inhibits gastric and pancreatic lipases in the gut lumen by binding their active serine site, so dietary triglycerides are not hydrolysed into absorbable free fatty acids and monoglycerides (US Xenical label).