سعر فليكسيلاكس 30 قرص 50 مجم / 500 مجم 2024

Film-coated tablets of diclofenac potassium 50 mg + methocarbamol 500 mg (Flexilax, Hikma Pharma), 30 tablets (3 strips of 10).

• Short-term (maximum 2 weeks) treatment of post-operative and post-traumatic pain and inflammation, painful gynaecological conditions, migraine attacks, adjunct in painful ENT inflammation, vertebral pain syndromes and non-articular rheumatism; adjunct to rest and physical therapy for acute painful musculoskeletal conditions.Population: Adults

• Methocarbamol: drowsiness, dizziness, lightheadedness, headache, nausea, blurred vision, rash/pruritus; rarely bradycardia, hypotension, jaundice, leukopenia.General active-ingredient information · DailyMed (U.S. NLM)

• History of asthma, urticaria or allergic-type reactions after aspirin or other NSAIDs.General active-ingredient information · DailyMed (U.S. NLM)
• In the setting of coronary artery bypass graft (CABG) surgery.General active-ingredient information · DailyMed (U.S. NLM)
• Hypersensitivity to methocarbamol or any component.General active-ingredient information · DailyMed (U.S. NLM)

• Diclofenac (NSAID) boxed warnings: increased risk of serious cardiovascular thrombotic events and of serious GI bleeding, ulceration and perforation.General active-ingredient information · DailyMed (U.S. NLM)
• Methocarbamol may impair mental/physical abilities and has additive CNS-depressant effects with alcohol and other CNS depressants; caution with driving or machinery.General active-ingredient information · DailyMed (U.S. NLM)

• Alcohol and other CNS depressantsAdditive CNS depression.DailyMed (U.S. NLM)
• Pyridostigmine bromideMethocarbamol may inhibit its effect; use with caution in myasthenia gravis patients on anticholinesterases.DailyMed (U.S. NLM)

• NSAID component: avoid at about 30 weeks of gestation and later; limit use between about 20 and 30 weeks (fetal renal dysfunction/oligohydramnios, ductus arteriosus closure).General active-ingredient information · DailyMed (U.S. NLM)
• Methocarbamol: safe use in pregnancy not established; reports of fetal and congenital abnormalities after in-utero exposure; should not be used in women who are or may become pregnant, particularly early pregnancy, unless benefit outweighs risk.General active-ingredient information · DailyMed (U.S. NLM)
• Methocarbamol and/or metabolites are excreted in dog milk; human milk excretion unknown; use caution when breastfeeding.General active-ingredient information · DailyMed (U.S. NLM)

• Diclofenac potassium: Inhibits COX-1 and COX-2, reducing prostaglandin synthesis.
• Methocarbamol: Mechanism not established; may be due to general CNS depression. No direct action on skeletal muscle (US label).