سعر هبديتوكس 0.2 مجم 2026

Lofexidine 0.2 mg film-coated tablets (Hopdetox, Arab Caps / Hope Pharma, Egypt), a central alpha-2 agonist for opioid withdrawal; pack of 20 tablets.

• Mitigation of opioid withdrawal symptoms to facilitate abrupt opioid discontinuation in adults.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common (≥ 10% and more frequent than placebo): orthostatic hypotension, bradycardia, hypotension, dizziness, somnolence, sedation and dry mouth.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• May cause hypotension, bradycardia and syncope; monitor vital signs before dosing; avoid in severe coronary insufficiency, recent myocardial infarction, cerebrovascular disease, chronic renal failure or marked bradycardia.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Prolongs the QT interval; avoid in congenital long QT syndrome; monitor ECG in electrolyte abnormalities, congestive heart failure, bradyarrhythmias, hepatic or renal impairment or with other QT-prolonging drugs (e.g. methadone).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Potentiates CNS depression from benzodiazepines, alcohol, barbiturates and other sedatives.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• MethadoneBoth prolong the QT interval; ECG monitoring is recommended with concomitant use.DailyMed (U.S. National Library of Medicine)
• Benzodiazepines, alcohol, barbiturates and other sedating drugsLofexidine potentiates CNS depressant effects of benzodiazepines and may potentiate those of alcohol, barbiturates and other sedatives.DailyMed (U.S. National Library of Medicine)

• Safety in pregnant women has not been established; in animal studies lofexidine caused reduced fetal weight, increased resorptions and litter loss at exposures below human exposure.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• No information on presence in human milk or effects on the breastfed infant; exercise caution in nursing women.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

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