سعر هيالجان 20 مجم / 2 مل حقنة مملوءة مسبقا 2025

Hyalgan sodium hyaluronate 20 mg/2 mL solution for intra-articular injection, one prefilled syringe (Fidia Italy > Phoenix Marketing Group); used for pain in knee osteoarthritis.

• Sustained relief of pain in osteoarthritis of the knee.Population: Adults including the elderlyHealth Products Regulatory Authority (HPRA), Ireland

• Local reactions (pain, swelling/effusion, warmth, redness) at the injection site, usually transient; aggravation of chronic inflammation in some cases; very rare intra-articular infection; rare systemic allergic reactions including isolated anaphylactic-like reactions; very rare rash, pruritus, urticaria; occasional fever.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland

• Known hypersensitivity to any ingredient or to avian proteins (the active ingredient is of avian origin); infection of the knee joint or infection/disease of the skin at the injection site.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland

• Remove joint effusion before injecting; examine for signs of acute inflammation before starting; avoid overburdening the joint immediately after injection; use only if the solution is clear.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland

• Other intra-articular injectionsShould not be administered simultaneously or mixed with other intra-articular injections (limited experience).Health Products Regulatory Authority (HPRA), Ireland
• Disinfectants containing quaternary ammonium saltsDo not use concomitantly; hyaluronic acid can precipitate in their presence.Health Products Regulatory Authority (HPRA), Ireland

• No embryotoxicity or teratogenicity in animal studies, but no experience in pregnant women; weigh expected benefit against potential fetal risk.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland
• Not expected to be present in human milk, but use caution in nursing mothers and weigh benefit against potential risk to the neonate.International label, same formulation · Health Products Regulatory Authority (HPRA), Ireland

• Sodium hyaluronate: Exogenous high-molecular-weight hyaluronic acid fraction; endogenous hyaluronic acid gives synovial fluid its viscosity and elasticity (lubricating and shock-absorbing properties); intra-articular administration into osteoarthritic joints improved joint function (Irish SmPC).