سعر ايبانتين 30 مجم / 5 مل معلق 125 مل 2024

Ipanten 30 mg/5 ml (T3A Pharma > Acdima International Trading): phenytoin 30 mg per 5 ml oral suspension, 125 ml bottle; a hydantoin antiepileptic.

• Control of tonic-clonic seizures, partial seizures or a combination; prevention and treatment of seizures during or after neurosurgery and/or severe head injury.Population: Adults and childrenelectronic medicines compendium (emc), MHRA-authorised SmPC
• Trigeminal neuralgia, as second-line therapy if carbamazepine is ineffective or not tolerated.Population: Adultselectronic medicines compendium (emc), MHRA-authorised SmPC

• Haematopoietic complications, some fatal, have occasionally been reported, including thrombocytopenia, leukopenia, granulocytopenia, agranulocytosis and pancytopenia.International label, equivalent formulation · electronic medicines compendium (emc), MHRA-authorised SmPC

• Hypersensitivity to phenytoin, other hydantoins or any excipient; co-administration with delavirdine (risk of loss of virological response and resistance).International label, equivalent formulation · electronic medicines compendium (emc), MHRA-authorised SmPC

• Not effective for absence (petit mal) seizures or seizures due to hypoglycaemia or other metabolic causes; abrupt withdrawal may precipitate status epilepticus, so reduce or substitute gradually (except in allergic or hypersensitivity reactions).International label, equivalent formulation · electronic medicines compendium (emc), MHRA-authorised SmPC
• Serious cutaneous reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis and DRESS, which can be fatal; HLA-B*1502 may be a risk factor for SJS/TEN in patients of Asian ancestry.International label, equivalent formulation · electronic medicines compendium (emc), MHRA-authorised SmPC
• Suicidal ideation and behaviour have been reported with antiepileptic agents; a meta-analysis showed a small increased risk.International label, equivalent formulation · electronic medicines compendium (emc), MHRA-authorised SmPC

• DelavirdineCo-administration is contraindicated: possible loss of virological response and resistance to delavirdine or the NNRTI class.electronic medicines compendium (emc), MHRA-authorised SmPC

• Phenytoin crosses the placenta; prenatal exposure is associated with about 6% major malformations (vs 2-3% in the general population), including orofacial clefts, cardiac and craniofacial defects, nail and digit hypoplasia and growth abnormalities (fetal hydantoin syndrome), and neurodevelopmental disorders have been reported.International label, equivalent formulation · electronic medicines compendium (emc), MHRA-authorised SmPC
• Women of childbearing potential should receive advice on risks; treatment should be reviewed when pregnancy is planned; avoid sudden discontinuation in pregnancy, and monotherapy is preferred where possible.International label, equivalent formulation · electronic medicines compendium (emc), MHRA-authorised SmPC
• Phenytoin appears in human milk in low concentrations; breastfeeding is not recommended during treatment.International label, equivalent formulation · electronic medicines compendium (emc), MHRA-authorised SmPC

• Phenytoin: Stabilises neuronal membranes and limits the spread of seizure activity, mainly by blocking voltage-dependent sodium channels.