سعر كولوكيورجيد 135 مجم 20 قرص 2022

Kolocurejed mebeverine 135 mg tablets, pack of 20 (Jedco, Egypt); antispasmodic used for irritable bowel syndrome.

• Symptomatic treatment of irritable bowel syndrome and related conditions (chronic irritable colon, spastic constipation, mucous colitis, spastic colitis), including colicky abdominal pain and cramps, persistent non-specific diarrhoea and flatulence (UK SmPC, equivalent 135 mg tablet).Population: Adultselectronic medicines compendium (emc)

• Postmarketing reports (frequency not known): hypersensitivity including anaphylactic reactions; urticaria, angioedema, face oedema and exanthema.International label, equivalent formulation · electronic medicines compendium (emc)

• Hypersensitivity to mebeverine or to any of the excipients.International label, equivalent formulation · electronic medicines compendium (emc)

• Consult a doctor before use if symptoms are new, or if the patient is over 40 years, has passed blood in the stools, nausea/vomiting, loss of appetite or weight, pallor and tiredness, severe constipation, fever, recent travel abroad, possible pregnancy, abnormal vaginal bleeding/discharge or difficulty/pain passing urine; seek advice if symptoms worsen or do not improve after 2 weeks.International label, equivalent formulation · electronic medicines compendium (emc)
• The UK reference tablet contains lactose; patients with rare hereditary galactose intolerance, total lactase deficiency or glucose-galactose malabsorption should not take it (excipients of the Egyptian tablet not verified).International label, equivalent formulation · electronic medicines compendium (emc)

• Alcohol (ethanol)No interaction studies performed except with alcohol; in vitro and animal studies showed no interaction between mebeverine hydrochloride and ethanol.electronic medicines compendium (emc)

• No or limited data in pregnant women; animal studies insufficient for reproductive toxicity. Mebeverine is not recommended during pregnancy.International label, equivalent formulation · electronic medicines compendium (emc)
• Unknown whether mebeverine or its metabolites are excreted in human milk; mebeverine should not be used during breast-feeding.International label, equivalent formulation · electronic medicines compendium (emc)

• Mebeverine: Musculotropic antispasmodic with a direct action on gastrointestinal smooth muscle without affecting normal gut motility; the exact mechanism is not known (UK SmPC 5.1).