سعر ليفوفرين 4مجم/4مل 5 امبولات 2024

Noradrenaline (norepinephrine) 4 mg/4 mL ampoules for intravenous use (after dilution), pack of 5 ampoules.

• Raise blood pressure in adult patients with severe, acute hypotension.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common: ischaemic injury, bradycardia, anxiety, transient headache, respiratory difficulty and extravasation necrosis at the injection site; hypertension, arrhythmias and pulmonary oedema can occur.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• None (US label lists no contraindications).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Tissue ischaemia: avoid use in hypovolaemia without volume correction and in mesenteric or peripheral vascular thrombosis; gangrene of extremities has occurred; extravasation can cause necrosis - infiltrate the area promptly with phentolamine 5-10 mg in 10-15 mL 0.9% sodium chloride.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Sudden cessation of the infusion may cause marked hypotension; norepinephrine may cause arrhythmias (especially with hypoxia or hypercarbia); the US product contains sodium metabisulfite, which may cause allergic-type reactions in sulfite-sensitive people.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• MAO inhibitors (including linezolid)Co-administration can cause severe, prolonged hypertension; monitor blood pressure if use cannot be avoided.DailyMed (U.S. National Library of Medicine)
• Tricyclic antidepressantsCan cause severe, prolonged hypertension; monitor for hypertension.DailyMed (U.S. National Library of Medicine)
• Antidiabetic drugsNorepinephrine can decrease insulin sensitivity and raise blood glucose; monitor glucose and consider antidiabetic dose adjustment.DailyMed (U.S. National Library of Medicine)

• Limited published data in pregnant women at delivery have not identified an increased risk of major birth defects, miscarriage or adverse maternal or fetal outcomes; life-sustaining therapy should not be withheld because of fetal concerns.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk; clinically relevant infant exposure is not expected given the short half-life and poor oral bioavailability.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Noradrenaline (norepinephrine): Peripheral vasoconstrictor (alpha-adrenergic action) and inotropic stimulator of the heart and dilator of coronary arteries (beta-adrenergic action).