سعر ليجنوفانس كريم 30 جم 2026

Lignovance cream 30 gm: Egyptian topical anaesthetic cream combining lidocaine (amide) and tetracaine (ester), from Nobel Pharm. Industries (per Egyptian price directories).

• Known sensitivity to lidocaine or tetracaine, to amide- or ester-type local anaesthetics, or to any other component of the product.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Hypersensitivity to para-aminobenzoic acid (PABA).General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Methaemoglobinaemia has been reported with local anaesthetics; patients with G6PD deficiency, congenital or idiopathic methaemoglobinaemia, cardiac or pulmonary compromise, infants under 6 months and those exposed to oxidising agents are more susceptible and need close monitoring.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Applying the cream for longer than recommended, over larger areas, or on broken or inflamed skin can increase absorption of lidocaine and tetracaine to toxic levels; not recommended on mucous membranes; consider all local anaesthetics used concurrently (effects additive).General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Used product may still contain large amounts of anaesthetic; keep and dispose of out of reach of children and pets.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Class I antiarrhythmic drugs (e.g. tocainide, mexiletine)Systemic toxic effects may be additive and potentially synergistic; use with caution.DailyMed (U.S. National Library of Medicine)
• Other local anaesthetic productsConsider the total amount absorbed from all formulations (additive systemic toxicity).DailyMed (U.S. National Library of Medicine)
• Drugs associated with methaemoglobinaemia (e.g. nitrates/nitrites, dapsone, sulfonamides, primaquine, phenytoin, acetaminophen)Increased risk of methaemoglobinaemia.DailyMed (U.S. National Library of Medicine)

• No data on use of the lidocaine/tetracaine cream in pregnant women; parenteral lidocaine data have not shown a drug-associated risk of major birth defects or miscarriage; tetracaine data are insufficient; systemic absorption from topical use is low.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• No data on tetracaine in human milk; lidocaine is present in milk after parenteral use (milk:plasma ratio 0.4-1.1) without a consistent pattern of adverse effects in breastfed infants; systemic absorption from topical use is low.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Lidocaine: Stabilises the neuronal membrane by inhibiting the ionic fluxes required for initiation and conduction of nerve impulses, producing local anaesthesia.
• Tetracaine: