سعر ليبوفوندين MCT/LCT 20% مستحلب للتسريب الوريدي 2022

Lipofundin MCT/LCT 20% emulsion for i.v. infusion (B. Braun Melsungen AG, Germany; distributed by Sunny Medical in Egypt): lipid emulsion of soya-bean oil and medium-chain triglycerides for parenteral nutrition.

• Source of calories and essential fatty acids for patients requiring parenteral nutrition.Population: Adults and paediatric patients requiring parenteral nutritionelectronic medicines compendium (eMC)

• Under correct use most reactions are very rare: hypercoagulability, allergic reactions, hyperlipidaemia, hyperglycaemia, metabolic acidosis, ketoacidosis, headache, drowsiness, hypertension/hypotension, flush, dyspnoea, cyanosis, nausea, vomiting, loss of appetite, erythema, sweating, back/bone/chest/lumbar pain, raised temperature, chills, fat overload syndrome; frequency not known: leucopenia, thrombocytopenia, cholestasis.International label, same formulation · electronic medicines compendium (eMC)

• Hypersensitivity to egg or soya-bean protein, soya-bean or peanut products or any ingredient; severe hyperlipidaemia; severe coagulopathy; severe hepatic insufficiency; intrahepatic cholestasis; severe renal insufficiency without renal replacement therapy; acute thromboembolic events; fat embolism; aggravating haemorrhagic diatheses; metabolic acidosis; plus general contraindications to parenteral nutrition (unstable circulation/shock, unstable metabolic conditions, acute phase of MI or stroke, uncorrected fluid/electrolyte disorders, decompensated cardiac insufficiency, acute pulmonary oedema).International label, same formulation · electronic medicines compendium (eMC)

• Monitor serum triglycerides regularly; reduce infusion rate if triglycerides exceed 4.6 mmol/L and interrupt if above 11.4 mmol/L; correct fluid, electrolyte and acid-base disorders before infusion; stop immediately at any sign of allergic reaction; give with adequate carbohydrates and amino acids (lipid alone may cause metabolic acidosis); caution in disturbed lipid metabolism (renal insufficiency, diabetes, pancreatitis, impaired hepatic function, hypothyroidism, sepsis).International label, same formulation · electronic medicines compendium (eMC)

• HeparinClinical doses of heparin cause transient release of lipoprotein lipase, initially increasing lipolysis followed by a transient decrease in triglyceride clearance.electronic medicines compendium (eMC)
• Coumarin derivativesSoya-bean oil contains vitamin K1 at a level not expected to influence coagulation significantly; nevertheless monitor coagulation status.electronic medicines compendium (eMC)

• Limited data; should only be administered to pregnant women after careful benefit-risk consideration.International label, same formulation · electronic medicines compendium (eMC)
• Components/metabolites are excreted in human milk but no effects on the infant are anticipated at therapeutic doses; in general, breastfeeding is not recommended for mothers receiving parenteral nutrition.International label, same formulation · electronic medicines compendium (eMC)

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