سعر موتيفال 20 قرص 0.5 مجم / 10 مجم 2024

Motival film-coated tablets: fluphenazine 0.5 mg + nortriptyline 10 mg (SmithKline Beecham), pack of 20.

• Historically used for mixed anxiety-depression / psychoneurotic states where a low-dose phenothiazine plus TCA is considered; confirm local indication on Egyptian label.Population: Adults (specialist)DrugBank — Fluphenazine / Nortriptyline

• Coma or severe CNS depression; known hypersensitivity to phenothiazines or TCAs; recent MI; concomitant MAOIs (for nortriptyline component); narrow-angle glaucoma / urinary retention risk (anticholinergic).General active-ingredient information · DrugBank — Fluphenazine / Nortriptyline

• Suicidality risk with antidepressants in young adults; tardive dyskinesia and NMS risk with fluphenazine; anticholinergic and cardiac conduction effects of nortriptyline; sedation — avoid alcohol/CNS depressants.General active-ingredient information · DrugBank — Fluphenazine / Nortriptyline

• Both components: use in pregnancy only if clearly needed; neonatal withdrawal/EPS possible with late pregnancy phenothiazine/TCA exposure. Avoid if possible during breastfeeding.General active-ingredient information · DrugBank — Fluphenazine / Nortriptyline

• Fluphenazine: Blocks postsynaptic dopamine D2 receptors in the CNS.
• Nortriptyline: Inhibits norepinephrine (and to a lesser extent serotonin) reuptake.