سعر نيكوتينيل تتس 10 10 cm2 2022

Nicotinell TTS 10 nicotine transdermal patch (10 cm2 releasing about 7 mg nicotine/24 h per UK SmPC); listed in Egypt by Novartis > GlaxoSmithKline.

• Relief and/or prevention of craving and nicotine withdrawal symptoms associated with tobacco dependence, to aid smokers wishing to quit or reduce prior to quitting; preferably with a behavioural support programme.Population: Adult smokers (12-17 years on medical advice)electronic medicines compendium (emc), UK
• Pregnant and lactating women making a quit attempt (when they cannot quit without pharmacological support).Population: Pregnant/lactating womenelectronic medicines compendium (emc), UK

• Application-site reactions are the most frequent (burning, oedema, erythema, irritation, pruritus, rash, urticaria, vesicles), leading to discontinuation in about 6% in trials. Very common: sleep disorders/abnormal dreams, headache, dizziness, nausea, vomiting. Common: agitation, anxiety, nervousness, tremor, palpitations, cough, pharyngitis, dyspnoea, dyspepsia, upper abdominal pain, diarrhoea, dry mouth, constipation, increased sweating. Uncommon/rare: tachycardia, hypertension, chest pain, arrhythmia; very rare anaphylaxis.International label, same product · electronic medicines compendium (emc), UK

• Non-smokers or occasional smokers; skin diseases that may complicate patch therapy; hypersensitivity to nicotine or any patch component.International label, same product · electronic medicines compendium (emc), UK

• Any risks of nicotine replacement therapy are substantially outweighed by the dangers of continued smoking. Haemodynamically unstable patients hospitalised with recent myocardial infarction, unstable/worsening angina, severe arrhythmias, uncontrolled hypertension or recent stroke should first try non-pharmacological cessation; if NRT is used, start under medical supervision.International label, same product · electronic medicines compendium (emc), UK
• Diabetes: monitor blood glucose more closely when starting NRT (catecholamine release can affect carbohydrate metabolism). Use with caution in uncontrolled hyperthyroidism or phaeochromocytoma, in patients on anticonvulsants or with a history of epilepsy, and in moderate to severe hepatic or severe renal impairment.International label, same product · electronic medicines compendium (emc), UK
• Danger in small children: doses tolerated by adult smokers can cause severe, possibly fatal, toxicity in children; keep out of sight and reach of children and dispose of used product carefully.International label, same product · electronic medicines compendium (emc), UK

• AdenosineNo clinically relevant interactions with NRT definitely established; nicotine may possibly enhance the haemodynamic effects of adenosine.electronic medicines compendium (emc), UK
• Drugs metabolised by CYP1A2 (e.g. theophylline, clozapine, olanzapine)Stopping smoking removes CYP1A2 induction by polycyclic aromatic hydrocarbons in tobacco smoke, which may raise blood levels of such drugs; dose adjustment may be needed.electronic medicines compendium (emc), UK

• Pregnant smokers should first be advised to stop without NRT. If the mother cannot quit without pharmacological support, NRT may be used because the risk to the fetus is lower than with smoking; use only if the expected benefit outweighs the potential risk.International label, same product · electronic medicines compendium (emc), UK
• Nicotine passes into breast milk and NRT should be avoided during breastfeeding; if needed, intermittent oral forms are preferred to patches; use only if the benefit outweighs the risk.International label, same product · electronic medicines compendium (emc), UK

• Nicotine: Nicotine is an agonist at nicotinic receptors in the peripheral and central nervous systems; the product replaces part of the nicotine obtained from tobacco and reduces withdrawal symptoms and the urge to smoke.