سعر اوستيوزوميت 4مجم/مل فيال 5 مل 2022

Zoledronic acid concentrate for intravenous infusion, one 5 ml vial (Global Pharmaceutical Industries / Penta Pharma, Egypt); third-generation bisphosphonate.

• Hypercalcaemia of malignancy; multiple myeloma and bone metastases from solid tumours (with standard antineoplastic therapy).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Hypersensitivity to zoledronic acid or any component; reactions include urticaria, angioedema and rarely anaphylaxis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Risk of clinically significant renal deterioration that may progress to renal failure; do not exceed 4 mg per dose and infuse over at least 15 minutes.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Zoledronic acid: Inhibits osteoclast-mediated bone resorption (blocks the mevalonate pathway and induces osteoclast apoptosis); binds to bone at sites of active remodelling.