سعر بيكواكنل كريم 2022

Topical pimecrolimus cream (calcineurin inhibitor) by Uniswab, marketed in Egypt for mild to moderate atopic dermatitis.

• Mild to moderate atopic dermatitis (eczema)Population: Non-immunocompromised adults and children 2 years and olderDailyMed (US NLM)

• Application-site burning is most common; also headache, nasopharyngitis, cough, influenza, pyrexia and viral skin infections.General active-ingredient information · DailyMed (US NLM)

• Hypersensitivity to pimecrolimus or any cream component.General active-ingredient information · DailyMed (US NLM)

• Long-term safety of topical calcineurin inhibitors not established; rare malignancy (skin, lymphoma) reported; avoid continuous long-term use and use in immunocompromised patients or children under 2 years.General active-ingredient information · DailyMed (US NLM)
• Resolve skin infections before use; may increase risk of varicella-zoster, herpes simplex and eczema herpeticum; minimize sun/UV exposure; do not use under occlusion.General active-ingredient information · DailyMed (US NLM)

• CYP3A inhibitors (e.g. erythromycin, itraconazole, ketoconazole, fluconazole, calcium channel blockers, cimetidine)Use with caution in widespread and/or erythrodermic disease; systemic interactions not expected but cannot be ruled out.DailyMed (US NLM)

• No adequate studies in pregnant women; use only if clearly needed.General active-ingredient information · DailyMed (US NLM)
• Unknown whether excreted in human milk; decide whether to discontinue nursing or the drug.General active-ingredient information · DailyMed (US NLM)

• Pimecrolimus: Binds macrophilin-12 (FKBP-12) and inhibits calcineurin, blocking T-cell activation and inflammatory cytokine release.