سعر بنتال اس ار 400مجم 20 قرص 2024

Pentoxifylline 400 mg sustained-release tablets (20) by Alexandria (Egypt), a hemorheologic agent used to improve peripheral blood flow.

• Intermittent claudication due to chronic occlusive arterial disease of the limbsPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Most frequent with the extended-release tablet: dyspepsia, nausea, dizziness, vomiting, headache, belching/bloating.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Recent cerebral and/or retinal haemorrhage; intolerance to pentoxifylline or other methylxanthines (caffeine, theophylline, theobromine).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Bleeding risk: monitor prothrombin time with warfarin and check haematocrit/haemoglobin in patients at bleeding risk; occasional angina, hypotension and arrhythmia reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Warfarin / vitamin K antagonistsIncreased prothrombin time/anticoagulant activity reported; monitor anticoagulation when starting or changing dose.DailyMed (U.S. National Library of Medicine)
• TheophyllineIncreased theophylline levels and toxicity in some individuals; monitor levels.DailyMed (U.S. National Library of Medicine)
• Strong CYP1A2 inhibitors (e.g. ciprofloxacin, fluvoxamine)May increase pentoxifylline exposure.DailyMed (U.S. National Library of Medicine)

• No adequate studies in pregnant women; use only if potential benefit justifies potential risk to the fetus (no malformations in rat/rabbit studies).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Pentoxifylline and metabolites are excreted in human milk; decide whether to discontinue nursing or the drug.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pentoxifylline: Lowers blood viscosity and improves erythrocyte flexibility, increasing blood flow to the affected microcirculation and tissue oxygenation; precise mode of action not fully defined.