سعر Pentalipsy 100 مجم 2022

Gabapentin 100 mg hard gelatin capsules (10) by Safe Pharma (Egypt), an antiepileptic GABA analogue also used for neuropathic pain.

• Postherpetic neuralgia in adultsDailyMed (U.S. National Library of Medicine)
• Adjunctive therapy of partial onset seizures, with and without secondary generalization, in adults and children 3 years and olderDailyMed (U.S. National Library of Medicine)

• Most common: dizziness, somnolence, peripheral oedema (PHN); somnolence, dizziness, ataxia, fatigue, nystagmus (epilepsy >12 years).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to gabapentin or its ingredients.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• DRESS/multiorgan hypersensitivity and anaphylaxis/angioedema: discontinue if suspected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Somnolence, dizziness and driving impairment; respiratory depression with opioids/CNS depressants or respiratory impairment.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Suicidal behaviour and ideation (antiepileptic class); do not stop abruptly (seizure risk, withdrawal symptoms).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Opioids (morphine, hydrocodone, oxycodone, buprenorphine)Respiratory depression and sedation, sometimes fatal; morphine increases gabapentin exposure.DailyMed (U.S. National Library of Medicine)
• Aluminium/magnesium hydroxide antacidsReduce gabapentin bioavailability by about 20%; take gabapentin at least 2 hours after.DailyMed (U.S. National Library of Medicine)

• Available cohort data have not indicated an increased risk of major birth defects or miscarriage; developmental toxicity in animals; neonatal withdrawal reported with concomitant opioids near delivery.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Gabapentin is secreted in human milk; effects on the breastfed infant are unknown.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Gabapentin: Structurally related to GABA without effect on GABA binding, uptake or degradation; binds with high affinity to the alpha-2-delta subunit of voltage-activated calcium channels; precise mechanism unknown.