سعر بيكسكولت 5 مجم 30 قرص 2026

Apixaban 5 mg film-coated tablets, pack of 30 (Mina Pharm, Egypt).

• Reduce the risk of stroke and systemic embolism in nonvalvular atrial fibrillation.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Prophylaxis of DVT after hip or knee replacement surgery; treatment of DVT and PE and reduction in the risk of recurrence.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (>1%) in adults are related to bleeding.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Active pathological bleeding; severe hypersensitivity to apixaban (e.g. anaphylaxis).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: premature discontinuation increases the risk of thrombotic events; spinal/epidural haematoma with neuraxial anaesthesia or puncture.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Can cause serious, potentially fatal bleeding; not recommended in patients with prosthetic heart valves.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Combined P-gp and strong CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, ritonavir)Reduce 5 mg or 10 mg twice-daily doses by 50%; avoid in patients already on 2.5 mg twice daily.DailyMed (U.S. National Library of Medicine)

• Limited data are insufficient to inform drug-associated risks; treatment may increase bleeding risk during pregnancy and delivery.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Breastfeeding is not recommended during treatment.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Apixaban: Selective, reversible inhibitor of free and clot-bound factor Xa and prothrombinase activity, decreasing thrombin generation; no direct effect on platelet aggregation (US label).