دواعي استعمال برازولوساب 30 مجم 20 قرص

Aripiprazole 30 mg tablets (Sabaa / Sovalue Pharma), an atypical antipsychotic.

• SchizophreniaDailyMed (US NLM)
• Acute treatment of manic and mixed episodes associated with bipolar I disorderDailyMed (US NLM)
• Adjunctive treatment of major depressive disorderDailyMed (US NLM)
• Irritability associated with autistic disorderDailyMed (US NLM)
• Tourette's disorderDailyMed (US NLM)

• Most common in adults (>=10%): nausea, vomiting, constipation, headache, dizziness, akathisia, anxiety, insomnia and restlessness.نشرة دولية لتركيبة مكافئة · DailyMed (US NLM)

• History of hypersensitivity reaction to aripiprazole (pruritus/urticaria to anaphylaxis).نشرة دولية لتركيبة مكافئة · DailyMed (US NLM)

• Boxed warning: increased mortality in elderly patients with dementia-related psychosis; not approved for this use.نشرة دولية لتركيبة مكافئة · DailyMed (US NLM)
• Boxed warning: increased risk of suicidal thoughts and behaviours in children, adolescents and young adults taking antidepressants (relevant to adjunctive MDD use).نشرة دولية لتركيبة مكافئة · DailyMed (US NLM)

• Strong CYP3A4/CYP2D6 inhibitors and strong CYP3A4 inducersDose adjustment of aripiprazole is recommended (reduce with inhibitors or in CYP2D6 poor metabolizers; increase with strong CYP3A4 inducers).DailyMed (US NLM)

• Aripiprazole is present in human milk and may decrease milk supply; monitor the breastfed infant for dehydration and inadequate weight gain.نشرة دولية لتركيبة مكافئة · DailyMed (US NLM)

• Mechanism unclear; efficacy may be mediated by partial agonism at D2 and 5-HT1A receptors and antagonism at 5-HT2A receptors (US label).