دواعي استعمال بريدابوكس 30 مجم 18 قرص

Dapoxetine (as hydrochloride) 30 mg film-coated tablets (Adwia) for premature ejaculation in adult men.

• Premature ejaculation in men aged 18-64 years meeting the SmPC diagnostic criteria (on-demand use only)الفئة: Adult men 18-64 yearsSwedish Medical Products Agency (Läkemedelsverket)

• Most common (dose related): nausea, dizziness, headache, diarrhoea, insomnia and fatigue; syncope and orthostatic hypotension reported.نشرة دولية لتركيبة مكافئة · Swedish Medical Products Agency (Läkemedelsverket)

• Significant cardiac conditions: heart failure NYHA II-IV, conduction abnormalities (AV block, sick sinus syndrome), significant ischaemic or valvular heart disease, history of syncope.نشرة دولية لتركيبة مكافئة · Swedish Medical Products Agency (Läkemedelsverket)
• History of mania or severe depression.نشرة دولية لتركيبة مكافئة · Swedish Medical Products Agency (Läkemedelsverket)
• Concomitant MAOIs, thioridazine, SSRIs/SNRIs/TCAs or other serotonergic medicines/herbals (e.g. tramadol, triptans, linezolid, lithium, St John's wort) or within 14 days of stopping them; potent CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, ritonavir).نشرة دولية لتركيبة مكافئة · Swedish Medical Products Agency (Läkemedelsverket)
• Moderate and severe hepatic impairment; hypersensitivity to dapoxetine or excipients.نشرة دولية لتركيبة مكافئة · Swedish Medical Products Agency (Läkemedelsverket)

• Orthostatic hypotension and syncope may occur; perform an orthostatic test before starting; patients should lie or sit down if prodromal symptoms occur and avoid driving or hazardous machinery.نشرة دولية لتركيبة مكافئة · Swedish Medical Products Agency (Läkemedelsverket)
• Not to be used with recreational drugs (risk of serotonin syndrome, arrhythmia) and not in men with erectile dysfunction using PDE5 inhibitors.نشرة دولية لتركيبة مكافئة · Swedish Medical Products Agency (Läkemedelsverket)

• MAOIs, thioridazine and serotonergic medicinesContraindicated (serotonergic toxicity); observe 14-day/7-day washout periods.Swedish Medical Products Agency (Läkemedelsverket)
• Potent CYP3A4 inhibitorsContraindicated.Swedish Medical Products Agency (Läkemedelsverket)

• Not indicated for use by women; animal studies do not indicate harmful effects on fertility or embryofetal development.نشرة دولية لتركيبة مكافئة · Swedish Medical Products Agency (Läkemedelsverket)

• Orthostatic test (supine and standing blood pressure and pulse) before initiating therapy.نشرة دولية لتركيبة مكافئة · Swedish Medical Products Agency (Läkemedelsverket)