دواعي استعمال برينيرفانكس 150مجم 20 كبسول
معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 63ج.م.
عن الدواء
Prenervanex 150 mg hard gelatin capsules, pack of 20 (Novartis > Sandoz), pregabalin, listed for epilepsy/neuropathic pain class.
دواعي الاستعمال
- Neuropathic pain associated with diabetic peripheral neuropathyDailyMed (U.S. National Library of Medicine)
- Postherpetic neuralgiaDailyMed (U.S. National Library of Medicine)
- Adjunctive therapy for partial-onset seizures in patients 1 month of age and olderDailyMed (U.S. National Library of Medicine)
- FibromyalgiaDailyMed (U.S. National Library of Medicine)
- Neuropathic pain associated with spinal cord injuryDailyMed (U.S. National Library of Medicine)
الآثار الجانبية
- Common adverse reactions include dizziness, somnolence, dry mouth, edema, blurred vision, weight gain and abnormal thinking (US label class effects).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
موانع الاستعمال
- Known hypersensitivity to pregabalin or any of its components; angioedema and hypersensitivity reactions have occurred.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطات
- Angioedema may be life-threatening; hypersensitivity; AEDs increase suicidal thoughts/behavior; taper gradually over ≥1 week to avoid withdrawal seizures; respiratory depression with CNS depressants or underlying respiratory compromise; dizziness and somnolence common.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
الحمل والرضاعة
- Observational studies suggest a possible small increase in overall major birth defects with pregabalin in pregnancy without a consistent specific pattern; enroll in NAAED pregnancy registry.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
كيف يعمل الدواء
- Binds the alpha2-delta subunit of voltage-gated calcium channels in CNS tissue; reduces release of excitatory neurotransmitters (US pregabalin label / PubChem).
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- DailyMed (U.S. National Library of Medicine)
- WHO Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index)
- PubChem (PUG REST)