دواعي استعمال بريموفيست 0.25ممول/مل 10مل

Gadoxetic acid (gadoxetate) 0.25 mmol/ml solution for injection in a 10 ml prefilled syringe for MRI of the liver (Bayer Healthcare / Soficopharm, Egypt). Primovist is the EU brand; US brand is Eovist.

• MRI of the liver to detect and characterize lesions in adults and pediatric patients (including term neonates) with known or suspected focal liver disease.الفئة: Adults and pediatric patients including term neonatesDailyMed (U.S. NLM)

• Most common (≥0.5%): nausea, headache, feeling hot, dizziness, back pain.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• History of severe hypersensitivity reactions to Eovist/gadoxetate.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• Risk of nephrogenic systemic fibrosis in patients with impaired renal function; hypersensitivity reactions including anaphylaxis; gadolinium retention in brain and other organs for months or years; avoid intrathecal use.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• Serum iron assays (complexometric/ferrocene methods)Caloxetate trisodium in the formulation can give falsely high or low serum iron values for up to 24 hours; perform tests before or ≥24 h after administration.DailyMed (U.S. NLM)

• GBCAs cross the placenta; animal data raise concern for fetal gadolinium retention; human epidemiological findings inconsistent. Use only if needed.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)
• Unknown if gadoxetate is in human milk; other GBCAs appear in milk at low levels. Consider interrupting breastfeeding and discarding milk for up to 10 hours after administration.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

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