دواعي استعمال بريمبران 10مجم/2مل 12 امبول

Metoclopramide 10 mg/2 ml solution for injection, pack of 12 ampoules (Sanofi, Egypt).

• Relief of symptoms of acute and recurrent diabetic gastroparesis; prophylaxis of vomiting with emetogenic cancer chemotherapy; prophylaxis of postoperative nausea and vomiting when nasogastric suction is undesirable; facilitation of small-bowel intubation.الفئة: AdultsDailyMed (U.S. NLM)

• Restlessness, drowsiness, fatigue; insomnia, headache, confusion, dizziness, depression with suicidal ideation; EPS more frequent at higher doses (about 70% drowsiness in chemotherapy patients at 1–2 mg/kg).نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• When GI motility stimulation might be dangerous (hemorrhage, obstruction, perforation); pheochromocytoma; known sensitivity; epilepsy or other drugs likely to cause extrapyramidal reactions.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• Rare neuroleptic malignant syndrome (hyperthermia, rigidity, altered consciousness, autonomic instability); tardive dyskinesia with prolonged use; extrapyramidal reactions.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• Anticholinergics and opioid analgesicsAntagonize the GI motility effects of metoclopramide. Additive sedation with alcohol, sedatives, hypnotics, narcotics and tranquilizers.DailyMed (U.S. NLM)

• Animal studies (IM/IV/SC/oral) showed no significant fetal harm; no adequate well-controlled human studies — use in pregnancy only if clearly needed (older US injection label wording).نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)
• Excreted in human milk; use caution in nursing mothers.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• ميتوكلوبراميد: مضاد لمستقبلات الدوبامين D2