دواعي استعمال برينوريلاكس 15مجم 30 كبسولة

Cyclobenzaprine 15 mg extended-release capsules, pack of 30 (Liptis, Egypt).

• Adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions. Use only short periods (up to two or three weeks). Not effective for spasticity of cerebral or spinal cord disease or cerebral palsy.الفئة: AdultsDailyMed (U.S. NLM)

• Most common (≥3% and greater than placebo): dry mouth, dizziness, fatigue, constipation, nausea, dyspepsia, somnolence.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• Hypersensitivity; concomitant MAO inhibitors or within 14 days of stopping them; acute recovery phase of myocardial infarction; arrhythmias, heart block, conduction disturbances or congestive heart failure; hyperthyroidism.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• Serotonin syndrome reported with other serotonergic drugs. Structurally related to tricyclic antidepressants (cardiovascular and CNS-depressant effects). Caution with urinary retention, angle-closure glaucoma, raised intraocular pressure and anticholinergic drugs.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

• MAO inhibitorsشديدLife-threatening interactions (hyperpyretic crisis, seizures, deaths) with MAO inhibitors; contraindicated.DailyMed (U.S. NLM)
• SSRIs, SNRIs, tramadol and other serotonergic drugsPostmarketing serotonin syndrome reported with combined use.DailyMed (U.S. NLM)

• Available case reports have not identified a drug-associated risk of major birth defects, miscarriage, or adverse maternal/fetal outcomes. In rats, decreased pup body weight and survival at cyclobenzaprine doses ≥10 mg/kg/day (about ≥3× MRHD of 30 mg/day).نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)
• No data on presence in human or animal milk, effects on the breastfed infant, or milk production.نشرة دولية لنفس التركيبة · DailyMed (U.S. NLM)

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