دواعي استعمال بروبريك 10مجم 10 اقراص
معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 16.5ج.م.
عن الدواء
Oral bambuterol 10 mg tablets; bambuterol is a prodrug of the beta-2 agonist terbutaline.
دواعي الاستعمال
- Management of asthma, bronchospasm and/or reversible airways obstruction.الفئة: Adultselectronic medicines compendium (emc), copy hosted by e-lactancia.org
الآثار الجانبية
- Very common: tremor, headache, restlessness. Common: palpitations, sleep disturbances. Uncommon: tachycardia, agitation. Also reported: hypokalaemia, hyperglycaemia, arrhythmias, hypersensitivity, paradoxical bronchospasm.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), copy hosted by e-lactancia.org
موانع الاستعمال
- Hypersensitivity to bambuterol or any excipient.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), copy hosted by e-lactancia.org
تحذيرات واحتياطات
- Use with caution in thyrotoxicosis and severe heart disease; rare myocardial ischaemia has been reported with beta-agonists.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), copy hosted by e-lactancia.org
- Potentially serious hypokalaemia may occur, especially in acute severe asthma; monitor serum potassium.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), copy hosted by e-lactancia.org
- Extra blood glucose monitoring is recommended initially in diabetic patients.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), copy hosted by e-lactancia.org
- Do not start or increase the dose during an acute asthma exacerbation; continue anti-inflammatory therapy.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), copy hosted by e-lactancia.org
- Contains lactose.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), copy hosted by e-lactancia.org
التداخلات الدوائية
- Suxamethonium (succinylcholine) and other muscle relaxants metabolised by plasma cholinesteraseBambuterol inhibits plasma cholinesterase and can prolong the muscle-relaxing effect up to 2-fold.electronic medicines compendium (emc), copy hosted by e-lactancia.org
- Beta-blockers (especially non-selective, including eye drops)May partly or totally inhibit the effect; should not normally be given together.electronic medicines compendium (emc), copy hosted by e-lactancia.org
- Diuretics, methylxanthines, corticosteroidsIncrease the risk of hypokalaemia.electronic medicines compendium (emc), copy hosted by e-lactancia.org
- Halogenated anaesthetics (e.g. halothane)Increased risk of cardiac arrhythmias; avoid halothane.electronic medicines compendium (emc), copy hosted by e-lactancia.org
الحمل والرضاعة
- Unknown whether bambuterol passes into milk; terbutaline does, but no effect on the infant is anticipated at therapeutic doses; weigh benefits.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), copy hosted by e-lactancia.org
المتابعة أثناء العلاج
- Monitor serum potassium in situations of hypokalaemia risk and blood glucose initially in diabetic patients.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc), copy hosted by e-lactancia.org
كيف يعمل الدواء
- Prodrug converted to terbutaline, a selective beta-2 agonist that relaxes bronchial smooth muscle; also reversibly inhibits plasma cholinesterase.
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- electronic medicines compendium (emc), copy hosted by e-lactancia.org
- WHO Collaborating Centre for Drug Statistics Methodology