دواعي استعمال بروبينسفير 250مجم 7 اقراص

Famciclovir 250 mg film-coated tablets, pack of 7.

• Treatment of recurrent herpes labialis (cold sores) in immunocompetent adultsالفئة: AdultsDailyMed (US NLM)
• Treatment of recurrent episodes and chronic suppression of recurrent genital herpes in immunocompetent adultsالفئة: AdultsDailyMed (US NLM)
• Herpes zoster (shingles) in immunocompetent adultsالفئة: AdultsDailyMed (US NLM)
• Recurrent orolabial or genital herpes in HIV-infected adultsالفئة: AdultsDailyMed (US NLM)

• Most common (>10% in at least one indication): headache and nausea.نشرة دولية لنفس التركيبة · DailyMed (US NLM)

• Known hypersensitivity to famciclovir, its components, or penciclovir cream.نشرة دولية لنفس التركيبة · DailyMed (US NLM)

• Acute renal failure has occurred in patients with renal disease given inappropriately high doses; reduce dosage in renal impairment.نشرة دولية لنفس التركيبة · DailyMed (US NLM)

• ProbenecidMay increase penciclovir levels; monitor for penciclovir toxicity.DailyMed (US NLM)

• Pharmacovigilance data have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal/fetal outcomes.نشرة دولية لنفس التركيبة · DailyMed (US NLM)
• No human milk data; penciclovir is present in the milk of lactating rats.نشرة دولية لنفس التركيبة · DailyMed (US NLM)

• Prodrug converted to penciclovir, whose triphosphate inhibits herpesvirus DNA polymerase and viral DNA synthesis.