دواعي استعمال بروفاليرج 1مجم 20 اقراص

Ketotifen 1 mg oral tablet by Rameda (Egypt), an H1-antihistamine/mast-cell stabiliser.

• Symptomatic treatment of allergic conditions including rhinitis and conjunctivitisHealth Products Regulatory Authority (HPRA), Ireland

• Common: agitation, irritability, insomnia, nervousness (particularly children). Uncommon: dizziness, dry mouth, cystitis. Rare: sedation, weight increase. Very rare: hepatitis, Stevens-Johnson syndrome, erythema multiforme.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA), Ireland

• Hypersensitivity to ketotifen or excipients; epilepsy; patients treated with oral antidiabetic agents; breastfeeding.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA), Ireland

• May lower the seizure threshold (very rare convulsions); thrombocytopenia reported with concurrent oral antidiabetics (biguanides); sedation may impair driving, especially in the first days; avoid alcohol.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA), Ireland

• CNS depressants, antihistamines, alcohol, anticoagulantsKetotifen may potentiate their effects.Health Products Regulatory Authority (HPRA), Ireland
• Oral antidiabetic agents (biguanides)Concomitant use should be avoided (thrombocytopenia reported).Health Products Regulatory Authority (HPRA), Ireland

• Limited human data; animal studies do not indicate harm. Should not be used in pregnancy unless the clinical condition requires ketotifen.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA), Ireland
• Excreted in rat milk; mothers receiving ketotifen should not breastfeed (contraindicated).نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA), Ireland