دواعي استعمال بروتام 10مجم/مل -5 مل فيال

Protamine sulphate 10 mg/ml intravenous injection, one 5 ml vial (50 mg) (Eipico, Egypt).

• Treatment of heparin overdosage.الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Sudden fall in blood pressure, bradycardia, transitory flushing and warmth, dyspnoea, nausea, vomiting, lassitude; back pain reported; severe reactions may occur.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Previous intolerance to protamine sulfate.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Rebound hyperheparinaemia or bleeding may occur 30 minutes to 18 hours after cardiac surgery despite full neutralisation; keep patients under close observation and give further doses if coagulation studies indicate.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Guide additional dosing by coagulation studies (e.g. heparin titration, activated clotting time) particularly after cardiac surgery.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Strongly basic protein that combines with strongly acidic heparin to form a stable salt, neutralising its anticoagulant activity (US label).