دواعي استعمال بيراليروزيس 10مجم 10 اقراص ممتد المفعول

Dalfampridine 10 mg extended-release film-coated tablets, box of 10; used to improve walking in multiple sclerosis (Atco Pharma, Egypt).

• Treatment to improve walking in adult patients with multiple sclerosis (demonstrated by an increase in walking speed).الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Most common (2% or more and above placebo): urinary tract infection, insomnia, dizziness, headache, nausea, asthenia, back pain, balance disorder, MS relapse, paresthesia, nasopharyngitis, constipation, dyspepsia, pharyngolaryngeal pain.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• History of seizure; moderate or severe renal impairment (CrCl 50 mL/min or less); history of hypersensitivity to dalfampridine or 4-aminopyridine (including anaphylaxis).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Can cause seizures; risk increases with dose; permanently discontinue if a seizure occurs.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Avoid concomitant use with other forms of 4-aminopyridine (fampridine), since the active ingredient is the same.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Can cause anaphylaxis and severe allergic reactions; discontinue and do not restart if they occur.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Other 4-aminopyridine products (fampridine)Avoid concomitant use; same active ingredient.DailyMed (U.S. National Library of Medicine)

• No adequate data on developmental risk in pregnant women; in animals, dosing during pregnancy and lactation reduced offspring viability and growth at clinically relevant doses.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk or effects on the breastfed infant; weigh benefits of breastfeeding against maternal need and potential infant risk.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Know the estimated creatinine clearance before initiating treatment.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)