دواعي استعمال بايريتراست 500مجم/50مل محلول

Paracetamol 500 mg/50 ml (10 mg/ml) solution for intravenous infusion, 1 container of 50 ml (Egypt).

• Management of mild to moderate pain and, with adjunctive opioids, moderate to severe pain in adults and children 2 years and older; reduction of fever in adults and children.DailyMed (U.S. National Library of Medicine)

• Most common in adults (5% or more and above placebo): nausea, vomiting, headache, insomnia.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to acetaminophen or excipients; severe hepatic impairment or severe active liver disease.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• Doses above those recommended may cause hepatic injury, liver failure and death; total daily dose includes all routes and products. Caution in hepatic disease, alcoholism, chronic malnutrition, severe hypovolaemia or severe renal impairment.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Risk of medication errors: avoid confusing mg and mL, dose by weight under 50 kg, program pumps correctly.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Rare serious skin reactions (AGEP, SJS, TEN) and hypersensitivity/anaphylaxis; discontinue at first sign.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)

• CYP2E1 inducers / ethanolMay alter acetaminophen metabolism and increase hepatotoxic potential.DailyMed (U.S. National Library of Medicine)
• WarfarinChronic oral acetaminophen 4000 mg/day increased INR in some warfarin-stabilised patients; more frequent INR assessment may be appropriate.DailyMed (U.S. National Library of Medicine)

• Published epidemiological studies of oral acetaminophen in pregnancy have not shown a clear association with birth defects, miscarriage or adverse maternal or fetal outcomes; animal studies showed some fetotoxicity at doses near the maximum human daily dose.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
• Acetaminophen passes rapidly into human milk (about 1-2% of the weight-adjusted maternal dose); one report of infant rash; weigh benefits of breastfeeding against maternal need.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)