دواعي استعمال راسيكاروكس 10مجم/جم اكياس

معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 5ج.م.

دواعي الاستعمال

Complementary symptomatic treatment of acute diarrhoea in infants older than 3 months and children, together with oral rehydration, when rehydration alone is insufficient and causal treatment is not possibleالفئة: Infants older than 3 months and children (<13 kg for the 10 mg sachet)Health Products Regulatory Authority (HPRA)

الآثار الجانبية

Common: headache. Uncommon: rash, erythema. Frequency unknown: erythema multiforme, angioedema and facial/lip/tongue/eyelid oedema, urticaria, pruritus, DRESS, anaphylactic shock.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA)

موانع الاستعمال

Hypersensitivity to racecadotril or any excipient.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA)
Contains sucrose: contraindicated in hereditary fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency (Irish product excipient; Egyptian excipients not confirmed).نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA)

تحذيرات واحتياطات

Racecadotril does not modify usual rehydration regimens; rehydration remains essential.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA)
Do not use with bloody or purulent stools and fever (possible invasive bacterial infection) or in antibiotic-associated diarrhoea; chronic diarrhoea not sufficiently studied.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA)
Angioedema (allergic or bradykinin-mediated) may occur; stop treatment, supervise until resolution and do not reintroduce. Careful risk/benefit assessment needed with ACE inhibitors.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA)
Skin reactions, sometimes severe, and severe cutaneous adverse reactions including DRESS have been reported; withdraw immediately if DRESS is suspected and never restart.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA)

التداخلات الدوائية

ACE inhibitors and other drugs causing bradykinin-mediated angioedema (e.g. angiotensin II antagonists, gliptins, mTOR inhibitors, sacubitril)Concomitant use may increase the risk of angioedema and is not recommended.Health Products Regulatory Authority (HPRA)

الحمل والرضاعة

No adequate human data; animal studies show no harmful effects, but racecadotril should not be given to pregnant women.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA)
Excretion in human milk unknown; should not be given to breastfeeding women.نشرة دولية لتركيبة مكافئة · Health Products Regulatory Authority (HPRA)

المصادر