دواعي استعمال راماسين 1.25مجم 7 اقراص

Ramipril 1.25 mg tablets, pack of 7 (T3A Pharma, Egypt); ACE inhibitor.

• Treatment of hypertension.الفئة: Adultselectronic medicines compendium (emc)
• Cardiovascular prevention in patients with manifest atherothrombotic cardiovascular disease or diabetes with at least one cardiovascular risk factor.الفئة: Adultselectronic medicines compendium (emc)
• Treatment of renal disease: incipient or manifest glomerular diabetic nephropathy and manifest non-diabetic glomerular nephropathy (macroproteinuria >= 3 g/day).الفئة: Adultselectronic medicines compendium (emc)
• Treatment of symptomatic heart failure.الفئة: Adultselectronic medicines compendium (emc)
• Secondary prevention after acute myocardial infarction with clinical signs of heart failure, started > 48 hours after the infarction.الفئة: Adultselectronic medicines compendium (emc)

• Safety profile includes persistent dry cough and hypotension-related reactions; serious reactions include angioedema, hyperkalaemia, renal or hepatic impairment, pancreatitis, severe skin reactions and neutropenia/agranulocytosis.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc)

• Hypersensitivity to ramipril, excipients or other ACE inhibitors; history of angioedema.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc)
• Concomitant sacubitril/valsartan; extracorporeal treatments with negatively charged surfaces.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc)
• Significant bilateral renal artery stenosis or stenosis in a single functioning kidney; hypotensive or haemodynamically unstable states.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc)
• Second and third trimesters of pregnancy.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc)
• With aliskiren-containing products in patients with diabetes or renal impairment (GFR < 60 ml/min/1.73 m2).نشرة دولية لنفس التركيبة · electronic medicines compendium (emc)

• Risk of acute hypotension and renal deterioration in patients with a strongly activated RAAS (e.g. severe hypertension, decompensated heart failure, volume depletion, diuretic therapy).نشرة دولية لنفس التركيبة · electronic medicines compendium (emc)
• Hyperkalaemia, especially with renal insufficiency, age > 70, uncontrolled diabetes, or potassium-raising drugs; monitor serum potassium.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc)
• Dual RAAS blockade (ACE inhibitor + ARB or aliskiren) is not recommended.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc)
• Non-productive persistent cough may occur and resolves on stopping.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc)

• Potassium salts, heparin, potassium-retaining diuretics, ARBs, trimethoprim, tacrolimus, ciclosporinHyperkalaemia may occur; close monitoring of serum potassium is required.electronic medicines compendium (emc)

• Not recommended because of insufficient information; prefer alternatives, especially for newborn or preterm infants.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc)

• Monitor renal function and serum potassium, particularly at initiation, with diuretics, and in at-risk patients.نشرة دولية لنفس التركيبة · electronic medicines compendium (emc)