دواعي استعمال رانكسابين 5مجم 21 قرص

Olanzapine 5 mg oral tablets (atypical antipsychotic), pack of 21 tablets (3 strips) marketed in Egypt.

• Schizophrenia (adults and adolescents 13-17 years)DailyMed (U.S. National Library of Medicine)
• Acute manic or mixed episodes of bipolar I disorder and maintenance treatmentDailyMed (U.S. National Library of Medicine)

• Most common in adult schizophrenia trials: postural hypotension, constipation, weight gain, dizziness, personality disorder, akathisia.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• No contraindications for olanzapine monotherapy in the US label; when combined with fluoxetine, lithium or valproate refer to those products' contraindications.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Boxed warning: elderly patients with dementia-related psychosis treated with antipsychotics have an increased risk of death; olanzapine is not approved for dementia-related psychosis.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Warnings include cerebrovascular adverse events in elderly dementia patients, suicide risk inherent in the illness, and metabolic changes (hyperglycaemia, dyslipidaemia, weight gain).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• CarbamazepineIncreases olanzapine clearance.DailyMed (U.S. National Library of Medicine)
• FluvoxamineMay increase olanzapine levels.DailyMed (U.S. National Library of Medicine)
• Diazepam / alcoholMay potentiate orthostatic hypotension.DailyMed (U.S. National Library of Medicine)

• Olanzapine is present in human milk; excess sedation, irritability, poor feeding and extrapyramidal symptoms have been reported in breastfed infants.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Antagonism mainly at dopamine D2 and serotonin 5-HT2A receptors (per Egyptian directory pharmacology note).