دواعي استعمال رافيمانتين 10مجم 30 اقراص

Memantine 10 mg film-coated tablets (NMDA receptor antagonist) for Alzheimer's dementia; 30 tablets (3 strips), Eva Pharma.

• Moderate to severe dementia of the Alzheimer's typeالفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Most common (at least 5% and greater than placebo): dizziness, headache, confusion and constipation.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to memantine hydrochloride or any excipient.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Conditions that raise urine pH (e.g. drugs, diet, renal tubular acidosis, severe urinary tract infection) may decrease urinary elimination of memantine and increase plasma levels.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Urine alkalinizers (e.g. carbonic anhydrase inhibitors, sodium bicarbonate)Reduced memantine clearance and increased plasma levels.DailyMed (U.S. National Library of Medicine)
• Other NMDA antagonists (amantadine, ketamine, dextromethorphan)Combined use not systematically evaluated; use with caution.DailyMed (U.S. National Library of Medicine)

• No adequate data on developmental risk in pregnant women; adverse developmental effects observed in animals at doses at or above those used clinically.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk, effects on the breastfed infant or milk production.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Uncompetitive (low-to-moderate affinity) NMDA receptor antagonist; persistent NMDA receptor activation by glutamate is thought to contribute to Alzheimer's disease symptoms (US label).