دواعي استعمال ريبيف 44مكجم/0.5مل حقن تحت الجلد 12 سرنجة معبأة

Interferon beta-1a 44 mcg/0.5 ml for subcutaneous injection (solution for injection in prefilled syringe), Merck Serono, distributed in Egypt.

• Relapsing forms of multiple sclerosis (clinically isolated syndrome, relapsing-remitting disease, active secondary progressive disease) in adultsالفئة: AdultsDailyMed (U.S. National Library of Medicine)

• Most common: injection site disorders, influenza-like symptoms (headache, fatigue, fever, rigors, chest pain, back pain, myalgia), abdominal pain, depression, elevated liver enzymes and haematologic abnormalities.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• History of hypersensitivity to natural or recombinant interferon beta, human albumin, or any other component of the formulation.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Depression and suicide: use with caution in patients with depression; consider stopping if depression develops.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Hepatic injury including rare hepatic failure; stop immediately if jaundice or liver dysfunction appears.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Anaphylaxis and other allergic reactions; injection site reactions including necrosis.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Decreased peripheral blood counts, thrombotic microangiopathy, pulmonary arterial hypertension and seizures have been reported.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Large cohort and published data have not identified a drug-associated risk of major birth defects with interferon beta in early pregnancy; data on low birth weight or miscarriage are inconsistent.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Interferon beta-1a is present in human milk at low levels; weigh benefits of breastfeeding against the mother's clinical need.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Blood cell counts and liver function tests at 1, 3 and 6 months after starting, then periodically; thyroid function every 6 months in patients with thyroid dysfunction history.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)