دواعي استعمال ريكاردوبريلدي 5/25مجم 14 اقراص

Fixed-dose tablet of ramipril 5 mg and hydrochlorothiazide 25 mg by Pharco, Egypt.

• Essential hypertension in patients for whom this combination is appropriate (not for initial therapy)Valeant Canada LP (Bausch Health Canada)

• Hypertension trials: headache, dizziness and fatigue/asthenia were the most frequent side effects; cough is a class effect.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to ramipril or any other ACE inhibitor (e.g. previous angioedema with an ACE inhibitor); combination with a neprilysin inhibitor (sacubitril) or within 36 hours of switching; co-administration with aliskiren in patients with diabetes.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
• Anuria; severe renal impairment or dialysis; severe hepatic impairment; hypersensitivity to thiazides or sulfonamides; hereditary/idiopathic angioedema; pregnancy and breastfeeding; clinically relevant electrolyte disturbances.نشرة دولية لنفس التركيبة · Valeant Canada LP (Bausch Health Canada)

• Fetal toxicity: drugs acting on the renin-angiotensin system can cause fetal injury and death; discontinue as soon as pregnancy is detected.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
• Angioedema (head/neck and intestinal), hypotension, hyperkalemia, renal impairment, hepatic failure, neutropenia/agranulocytosis and persistent dry cough may occur.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)

• Potassium-sparing diuretics, potassium supplements and other potassium-raising agentsRisk of hyperkalemia; monitor serum potassium.DailyMed (U.S. National Library of Medicine)
• LithiumIncreased serum lithium and toxicity; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• NSAIDs including COX-2 inhibitorsMay worsen renal function and attenuate the antihypertensive effect.DailyMed (U.S. National Library of Medicine)
• mTOR inhibitors and other drugs causing angioedemaIncreased angioedema risk.DailyMed (U.S. National Library of Medicine)

• Contraindicated during breastfeeding (ACE inhibitor and thiazides reported in human milk).نشرة دولية لنفس التركيبة · Valeant Canada LP (Bausch Health Canada)

• Monitor serum potassium (especially with renal impairment, diabetes or potassium-raising drugs) and renal function; establish baseline renal function.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)