دواعي استعمال ريسبتولوك 300 مجم 20كبسولة

Nizatidine 300 mg oral capsules (20 capsules), a histamine H2-receptor antagonist used for peptic ulcer and gastro-oesophageal reflux disease.

• Treatment of active duodenal ulcer for up to 8 weeks.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
• Maintenance therapy after healing of active duodenal ulcer at a reduced dose (150 mg at bedtime).الفئة: AdultsDailyMed (U.S. National Library of Medicine)
• Treatment of endoscopically diagnosed oesophagitis (erosive and ulcerative) and associated heartburn due to GERD for up to 12 weeks.الفئة: AdultsDailyMed (U.S. National Library of Medicine)
• Treatment of active benign gastric ulcer for up to 8 weeks (exclude malignancy first).الفئة: AdultsDailyMed (U.S. National Library of Medicine)

• In placebo-controlled trials, anaemia and urticaria were significantly more common than with placebo; frequently reported events included headache, abdominal pain, diarrhoea, nausea, rhinitis and dizziness.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Hepatocellular injury with elevated liver enzymes, hepatitis and jaundice have been reported; rare thrombocytopenia, anaphylaxis, gynaecomastia and reversible mental confusion.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to nizatidine, and history of hypersensitivity to other H2-receptor antagonists (cross-sensitivity observed).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Symptomatic response does not preclude gastric malignancy.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• Dose should be reduced in moderate to severe renal insufficiency because nizatidine is excreted mainly by the kidney.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• False-positive urobilinogen tests with Multistix may occur during therapy.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Aspirin (very high doses)With aspirin 3,900 mg daily, serum salicylate levels increased when nizatidine 150 mg twice daily was given concurrently.DailyMed (U.S. National Library of Medicine)

• Animal reproduction studies showed no harm to the fetus, but there are no adequate and well-controlled studies in pregnant women; use only if clearly needed.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
• About 0.1% of an oral dose is secreted in human milk; decide whether to discontinue nursing or the drug, considering the importance of the drug to the mother.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Renal function may be monitored in elderly patients, as nizatidine is substantially excreted by the kidney.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)

• Competitive, reversible inhibitor of histamine at H2 receptors of gastric parietal cells, reducing basal, nocturnal and stimulated gastric acid secretion.