دواعي استعمال ريكورمون 4000وحدة دولية 6 سرنجات معبأة للحقن

Epoetin beta (recombinant human erythropoietin) 4000 IU solution for injection in pre-filled syringes (6 syringes), used mainly for anaemia of chronic kidney disease and chemotherapy-induced anaemia.

• Treatment of symptomatic anaemia associated with chronic renal failure.الفئة: Adult and paediatric patientselectronic medicines compendium (eMC)
• Prevention of anaemia of prematurity in infants (birth weight 750-1500 g, gestational age <34 weeks).الفئة: Premature infantselectronic medicines compendium (eMC)
• Treatment of symptomatic anaemia in adults with non-myeloid malignancies receiving chemotherapy.الفئة: Adultselectronic medicines compendium (eMC)
• Increasing the yield of autologous blood in patients in a predonation programme.الفئة: Adultselectronic medicines compendium (eMC)

• Common: hypertension and headache (CKD patients); thromboembolic events and hypertension in cancer patients.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)
• Rare: shunt thrombosis in haemodialysis patients; hypersensitivity reactions; very rare PRCA.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)

• Hypersensitivity to the active substance or excipients.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)
• Poorly controlled hypertension.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)
• In autologous blood predonation: myocardial infarction or stroke in the month before treatment, unstable angina, or increased risk of deep vein thrombosis.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)

• Pure red cell aplasia caused by neutralising anti-erythropoietin antibodies has been reported; discontinue and do not switch to another ESA if PRCA is diagnosed.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)
• Blood pressure may rise, including hypertensive crisis with encephalopathy-like symptoms and seizures; monitor and treat blood pressure.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)
• Severe cutaneous adverse reactions including Stevens-Johnson syndrome and toxic epidermal necrolysis have been reported with epoetins.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)
• In CKD, haemoglobin should not be targeted above 12 g/dL because of increased risk of death and serious cardiovascular events.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)
• In cancer patients, ESAs may promote tumour growth and are associated with increased thromboembolic risk; weigh benefit and risk.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)
• Correct iron, folic acid and vitamin B12 deficiency; iron supplementation is recommended for patients with low ferritin.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)
• Contains phenylalanine; may be harmful to people with phenylketonuria.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)
• Storage: refrigerate at 2-8 C in the outer carton to protect from light; for ambulatory use may be kept at up to 30 C for a single period of up to 3 days.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)

• No clinical data on exposed pregnancies; animal studies show no direct harmful effects; caution when prescribing to pregnant women.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)
• Unknown whether epoetin beta is excreted in human milk; decide whether to continue/discontinue breastfeeding or therapy considering benefit to child and mother.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)

• Monitor blood pressure, haemoglobin, iron status, platelet counts regularly during the first 8 weeks, and serum potassium and phosphate.نشرة دولية لنفس التركيبة · electronic medicines compendium (eMC)

• Recombinant glycoprotein identical in action to endogenous erythropoietin; stimulates erythroid progenitor proliferation and differentiation.