دواعي استعمال ريكتيفارد 20مجم 2 قرص
معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 19ج.م.
عن الدواء
Vardenafil 20 mg film-coated tablets (2), a phosphodiesterase type 5 (PDE5) inhibitor for erectile dysfunction in men.
دواعي الاستعمال
- Treatment of erectile dysfunction.الفئة: Adult menDailyMed (U.S. National Library of Medicine)
الآثار الجانبية
- Most common (>=2%): headache (15%), flushing (11%), rhinitis (9%), dyspepsia (4%), accidental injury, sinusitis, flu syndrome, dizziness, increased CPK, nausea, back pain.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
موانع الاستعمال
- Use with nitrates or nitric oxide donors in any form (risk of severe hypotension).نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Coadministration with guanylate cyclase stimulators such as riociguat.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطات
- Assess cardiovascular status; sexual activity carries cardiac risk; not recommended where sexual activity is inadvisable.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Prolonged erection over 4 hours or priapism: seek emergency care.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Sudden loss of vision (possible NAION): stop use and seek medical attention.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Sudden decrease or loss of hearing: stop use and seek prompt medical attention.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- QT prolongation: avoid in congenital long QT and with class IA (e.g. quinidine, procainamide) or class III (e.g. amiodarone, sotalol) antiarrhythmics.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Use with alpha-blockers only when patient is stable on alpha-blocker therapy; start at lowest dose.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Not indicated for use in women or children.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائية
- Nitrates / nitric oxide donorsContraindicated: potentiates hypotensive effects.DailyMed (U.S. National Library of Medicine)
- Ritonavir, cobicistat-boosted regimensDo not exceed a single 2.5 mg dose in a 72-hour period.DailyMed (U.S. National Library of Medicine)
- Indinavir, saquinavir, atazanavir, ketoconazole 400 mg, itraconazole 400 mg, clarithromycinDo not exceed a single 2.5 mg dose in a 24-hour period.DailyMed (U.S. National Library of Medicine)
- Ketoconazole 200 mg, itraconazole 200 mg, erythromycinDo not exceed a single 5 mg dose in a 24-hour period.DailyMed (U.S. National Library of Medicine)
- Alpha-blockersAdditive blood-pressure lowering; start vardenafil at 5 mg (2.5 mg with ritonavir-type inhibitors) in patients stable on alpha-blockers.DailyMed (U.S. National Library of Medicine)
- Class IA/III antiarrhythmicsAvoid due to QT prolongation.DailyMed (U.S. National Library of Medicine)
- RiociguatContraindicated: hypotension.DailyMed (U.S. National Library of Medicine)
الحمل والرضاعة
- Vardenafil is not indicated for use in females.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
كيف يعمل الدواء
- Inhibits cGMP-specific PDE5 in the corpus cavernosum, enhancing nitric oxide-mediated smooth muscle relaxation and penile erection upon sexual stimulation.
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- DailyMed (U.S. National Library of Medicine)