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دواعي استعمال ريفوباسين 40مجم 3 امبول

معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 6ج.م.

دواعي الاستعمال
  • Serious infections caused by susceptible strains of Pseudomonas aeruginosa, Proteus species, E. coli, Klebsiella-Enterobacter-Serratia, Citrobacter and Staphylococcus species (e.g. neonatal sepsis, septicaemia, meningitis, urinary, respiratory, gastrointestinal, skin, bone and soft-tissue infections).DailyMed (U.S. National Library of Medicine)
الآثار الجانبية
  • Nephrotoxicity (casts, cells or protein in urine, rising BUN/creatinine, oliguria) and eighth-nerve toxicity (dizziness, vertigo, tinnitus, hearing loss); also peripheral neuropathy, rash, urticaria, nausea, vomiting, fever, headache and others.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
موانع الاستعمال
  • Hypersensitivity to gentamicin; a history of hypersensitivity or serious toxic reactions to other aminoglycosides may contraindicate use (cross-sensitivity).نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطات
  • Boxed warning: potential nephrotoxicity and neurotoxicity (vestibular and auditory ototoxicity, usually irreversible), greater with renal impairment, high doses or prolonged therapy; keep patients under close clinical observation.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
  • Aminoglycosides can cause fetal harm when given to a pregnant woman.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
  • Neuromuscular blockade and respiratory paralysis are possible, especially with anaesthetics, neuromuscular blockers or massive citrated blood transfusion; use with caution in myasthenia gravis or parkinsonism.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
  • The US product contains sodium metabisulfite (sulfite allergy risk); whether the Egyptian ampoules contain sulfite was not verified.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائية
  • Other neurotoxic/nephrotoxic drugs (e.g. cephalosporins, other aminoglycosides)Increased nephrotoxicity has been reported with concomitant aminoglycosides and cephalosporins.DailyMed (U.S. National Library of Medicine)
  • Neuromuscular blocking agents and anaesthetics (e.g. succinylcholine)Possible neuromuscular blockade and respiratory paralysis.DailyMed (U.S. National Library of Medicine)
الحمل والرضاعة
  • Aminoglycosides cross the placenta; congenital deafness has been reported with streptomycin. Animal studies with gentamicin showed no fetal harm. If used in pregnancy the patient should be informed of the potential hazard.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
المتابعة أثناء العلاج
  • Monitor renal and eighth cranial nerve function, urinalysis, BUN/serum creatinine or creatinine clearance; measure peak and trough serum concentrations (avoid prolonged peaks above 12 mcg/mL and troughs above 2 mcg/mL); serial audiograms where feasible.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
كيف يعمل الدواء
  • Bactericidal; inhibits normal bacterial protein synthesis in susceptible organisms.
سعر ريفوباسين 40مجم 3 امبولالمثائل والبدائل

المصادر