دواعي استعمال ريجيماكس 30 كبسولة 120 مجم
معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 240ج.م.
دواعي الاستعمال
- Obesity management including weight loss and weight maintenance with a reduced-calorie diet, and reduction of the risk of weight regain; for BMI >=30 kg/m2, or >=27 kg/m2 with other risk factors.DailyMed (U.S. National Library of Medicine)
الآثار الجانبية
- Commonly observed GI events: oily spotting, flatus with discharge, faecal urgency, fatty/oily stool, oily evacuation, increased defecation and faecal incontinence.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
موانع الاستعمال
- Pregnancy; chronic malabsorption syndrome; cholestasis; known hypersensitivity to orlistat or any component.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطات
- Rare severe liver injury (hepatocellular necrosis, acute hepatic failure); stop and check liver tests if symptoms of hepatic dysfunction occur.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
- Increased urinary oxalate with oxalate nephrolithiasis and oxalate nephropathy with renal failure reported; monitor renal function in at-risk patients.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
- Reduces absorption of some fat-soluble vitamins and beta-carotene; substantial weight loss may increase cholelithiasis risk; exclude organic causes of obesity; GI events increase with high-fat diets.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائية
- CyclosporineReduced cyclosporine levels; do not co-administer simultaneously; give cyclosporine 3 hours after orlistat and monitor levels.DailyMed (U.S. National Library of Medicine)
- LevothyroxineHypothyroidism reported; separate administration by at least 4 hours and monitor thyroid function.DailyMed (U.S. National Library of Medicine)
- Warfarin and other anticoagulantsDecreased vitamin K absorption; altered INR reported; monitor coagulation parameters.DailyMed (U.S. National Library of Medicine)
- AmiodaroneReduced exposure to amiodarone and desethylamiodarone; reduced effect possible.DailyMed (U.S. National Library of Medicine)
- Antiepileptic drugsConvulsions reported; monitor seizure frequency/severity.DailyMed (U.S. National Library of Medicine)
- Antiretroviral drugsLoss of virological control reported; monitor HIV RNA and stop orlistat if viral load increases.DailyMed (U.S. National Library of Medicine)
الحمل والرضاعة
- Contraindicated in pregnancy: weight loss offers no benefit to a pregnant woman and may result in fetal harm; animal studies showed no embryotoxicity or teratogenicity.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
- Not known whether orlistat is present in human milk; use caution in nursing women.نشرة دولية لتركيبة مكافئة · DailyMed (U.S. National Library of Medicine)
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- DailyMed (U.S. National Library of Medicine)