دواعي استعمال ريافيرون 3م.وحدة امبول
معلومات من نشرات دوائية ومراجع موثقة، مع مصدر كل معلومة. السعر الحالي: 45ج.م.
دواعي الاستعمال
- Hairy cell leukaemia.ANSM - Base de donnees publique des medicaments (ecodex)
- Philadelphia-chromosome-positive chronic myeloid leukaemia in chronic phase.ANSM - Base de donnees publique des medicaments (ecodex)
- Cutaneous T-cell lymphoma.ANSM - Base de donnees publique des medicaments (ecodex)
- Histologically proven chronic hepatitis B in adults with markers of viral replication.ANSM - Base de donnees publique des medicaments (ecodex)
- Histologically proven chronic hepatitis C in adults (efficacy increased in combination with ribavirin).ANSM - Base de donnees publique des medicaments (ecodex)
- Chronic hepatitis C, hairy cell leukaemia, AIDS-related Kaposi sarcoma and chronic myelogenous leukaemia (directory listing).
الآثار الجانبية
- Anorexia, nausea, flu-like symptoms (fever, chills); leucopenia, thrombocytopenia, anaemia; thyroid disorders; cardiovascular events (hypotension, arrhythmia) were reported, mainly at high doses in cancer patients.نشرة دولية لتركيبة مكافئة · ANSM - Base de donnees publique des medicaments (ecodex)
موانع الاستعمال
- Hypersensitivity to recombinant interferon alfa-2a or excipients.نشرة دولية لتركيبة مكافئة · ANSM - Base de donnees publique des medicaments (ecodex)
- Severe pre-existing cardiac disease or history of cardiac disease.نشرة دولية لتركيبة مكافئة · ANSM - Base de donnees publique des medicaments (ecodex)
- Severe renal, hepatic or bone-marrow dysfunction; uncontrolled epilepsy or CNS dysfunction.نشرة دولية لتركيبة مكافئة · ANSM - Base de donnees publique des medicaments (ecodex)
- Advanced decompensated chronic hepatitis or cirrhosis; chronic hepatitis recently or currently treated with immunosuppressants.نشرة دولية لتركيبة مكافئة · ANSM - Base de donnees publique des medicaments (ecodex)
- Benzyl-alcohol-containing solution contraindicated in premature infants, neonates, infants and children up to 3 years.نشرة دولية لتركيبة مكافئة · ANSM - Base de donnees publique des medicaments (ecodex)
تحذيرات واحتياطات
- Severe psychiatric reactions including depression, suicidal ideation, suicide attempts and suicide may occur; monitor all patients for depression.نشرة دولية لتركيبة مكافئة · ANSM - Base de donnees publique des medicaments (ecodex)
- Discontinue if hypersensitivity occurs; serious bacterial, viral or fungal infections have been reported; immunostimulation may reduce efficacy of immunosuppression and graft rejection has been reported.نشرة دولية لتركيبة مكافئة · ANSM - Base de donnees publique des medicaments (ecodex)
الحمل والرضاعة
- Men and women receiving treatment should use effective contraception; use in pregnancy only if benefit justifies potential fetal risk (abortifacient effect in monkeys). Ribavirin combination is contraindicated in pregnancy.نشرة دولية لتركيبة مكافئة · ANSM - Base de donnees publique des medicaments (ecodex)
المتابعة أثناء العلاج
- Monitor for signs of depression and for infections, especially in neutropenic patients.نشرة دولية لتركيبة مكافئة · ANSM - Base de donnees publique des medicaments (ecodex)
كيف يعمل الدواء
- Induces cellular resistance to viral infection and modulates immune effectors; antitumour mechanism not fully known (Roferon-A SmPC 5.1).
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- ANSM - Base de donnees publique des medicaments (ecodex)